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CHR-6494 - ≥98% , CAS No.1333377-65-3

CAS: 1333377-65-3 Cat. No.: C124894 Fórmula: C16H16N6 Peso molecular: 292.34
COA
CHR-6494 - ≥98% CAS No(1333377-65-3) by Aladdin Scientific
Disponível para encomenda
GRADE & PURITY ≥98%
Synonyms
FT-0734501 | NCGC00370724-05 | 1333377-65-3 | CHR6494 | CHR-6494 | HY-15217 | BDBM50587785 | DTXSID90742629 | AKOS025149446 | F84874 | A899134 | 3-(1H-Indazol-5-yl)-N-propylimidazo-[1,2-b]pyridazin-6-amine | 3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyrid
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
Alemanha (EU)
USA*
Price
Qty
5mg
C124894-5mg
Sob encomenda · 8–12 semanas

43,30€

64,99€
Gravar 21,69 € (33.38%)
10mg
C124894-10mg
Sob encomenda · 8–12 semanas

65,86€

98,84€
Gravar 32,97 € (33.36%)
25mg
C124894-25mg
Sob encomenda · 8–12 semanas

130,07€

195,15€
Gravar 65,08 € (33.35%)
50mg
C124894-50mg
Sob encomenda · 8–12 semanas

238,54€

358,29€
Gravar 119,75 € (33.42%)
100mg
C124894-100mg
Sob encomenda · 8–12 semanas

404,28€

606,46€
Gravar 202,18 € (33.34%)
Enter a quantity for the sizes you want to add.
Bulk / Custom
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SDS
Safety data
COA
Certificate
DS
Datasheet
SP
Spec sheet
Specifications Nomes e identificadores Documentation Advanced Data Taxonomic Classification Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Calculadoras de soluções Revisões
🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos
FT-0734501 | NCGC00370724-05 | 1333377-65-3 | CHR6494 | CHR-6494 | HY-15217 | BDBM50587785 | DTXSID90742629 | AKOS025149446 | F84874 | A899134 | 3-(1H-Indazol-5-yl)-N-propylimidazo-[1,2-b]pyridazin-6-amine | 3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyrid
Especificações e pureza
≥98%
Mecanismos bioquímicos e fisiológicos
CHR-6494 is a potent and selective Haspin (Haploid Germ Cell-Specific Nuclear Protein Kinase) inhibitor that blocks H3T3ph phosphorylation. CHR-6494 causes cell cycle arrest in G2/M and subsequent apoptosis. CHR-6494 causes an abnormal duplication of cent
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Tipo de ação
INHIBITOR
Pureza
≥98%
Nomes e identificadores
Sorrisos canónicosCCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1
IUPAC Name3-(1H-indazol-5-yl)-N-propylimidazo[1,2-b]pyridazin-6-amine
InChIKeyCZZCAOGIEGXMBZ-UHFFFAOYSA-N
INCHI1S/C16H16N6/c1-2-7-17-15-5-6-16-18-10-14(22(16)21-15)11-3-4-13-12(8-11)9-19-20-13/h3-6,8-10H,2,7H2,1H3,(H,17,21)(H,19,20)
SMILES isoméricas CCCNC1=NN2C(=NC=C2C3=CC4=C(C=C3)NN=C4)C=C1
CAS alternativo 1458630-17-5 （TFA salt）
Peso molecular 292.34
Reaxy-Rn 29788281
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29788281&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClasseBenzopyrazoles
SubclassIndazoles
Intermediate Tree Nodes Not available
Direct ParentIndazoles
Alternative Parents Aminopyridazines  N-substituted imidazoles  Imidolactams  Benzenoids  Pyrazoles  Heteroaromatic compounds  Azacyclic compounds  Hydrocarbon derivatives  Amines  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Benzopyrazole - Indazole - Aminopyridazine - N-substituted imidazole - Pyridazine - Benzenoid - Imidolactam - Pyrazole - Heteroaromatic compound - Imidazole - Azole - Azacycle - Organonitrogen compound - Amine - Hydrocarbon derivative - Organic nitrogen compound - Aromatic heteropolycyclic compound
DescriçãoThis compound belongs to the class of organic compounds known as indazoles. These are compounds containing an indazole, which is structurally characterized by a pyrazole fused to a benzene.
External Descriptors Not available
Estrutura 3D
Modelo de Estrutura Química Interativa





Alvos associados (humanos)
ABL1 Tclin Tyrosine-protein kinase ABL (18331 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GSK3B Tclin Glycogen synthase kinase-3 beta (11785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PIM1 Tchem Serine/threonine-protein kinase PIM1 (9629 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
JAK3 Tclin Tyrosine-protein kinase JAK3 (8349 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CSNK1E Tclin Casein kinase I epsilon (1412 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
HASPIN Tchem Serine/threonine-protein kinase haspin (906 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CDK5 Tchem Cyclin-dependent kinase 5/CDK5 activator 1 (3697 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Alvos associados (não humanos)
Dyrk1a Dual specificity tyrosine-phosphorylation-regulated kinase 1A (1629 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Clk1 Dual specificity protein kinase CLK1 (404 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de ação
Certificados（CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriedades químicas e físicas
SolubilidadeDMSO
Peso molecular292.340 g/mol
XLogP32.800
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count4
Rotatable Bond Count4
Exact Mass292.144 Da
Monoisotopic Mass292.144 Da
Topological Polar Surface Area70.900 Ų
Heavy Atom Count22
Formal Charge0
Complexity378.000
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluções
Revisões

Avaliações dos Clientes

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