≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Information
CK1-IN-1 CK1-IN-1 (PUN51207, Compound 1C) is an inhibitor of casein kinase 1 (CK1) with IC50 of 15 nM, 16 nM and 73 nM for CK1δ, CK1ε and p38α MAPK, respectively.
Targets
CK1δ (Cell-free assay); CK1ε (Cell-free assay); p38αMAPK (Cell-free assay) 15 nM; 16 nM; 73 nM
| Pubchem Sid | 504772861 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/504772861 |
| Sorrisos canónicos | C1=CC=C2C(=C1)C=CC(=C2F)C3=NC(=C(N3)C4=CC=NC=C4)C5=CC=C(C=C5)F |
| IUPAC Name | 4-[2-(1-fluoronaphthalen-2-yl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]pyridine |
| InChIKey | PUQAFIILJICJRR-UHFFFAOYSA-N |
| INCHI | 1S/C24H15F2N3/c25-18-8-5-16(6-9-18)22-23(17-11-13-27-14-12-17)29-24(28-22)20-10-7-15-3-1-2-4-19(15)21(20)26/h1-14H,(H,28,29) |
| SMILES isoméricas | C1=CC=C2C(=C1)C=CC(=C2F)C3=NC(=C(N3)C4=CC=NC=C4)C5=CC=C(C=C5)F |
| Peso molecular | 383.39 |
| Reaxy-Rn | 28532087 |
| Reaxys-RN_link_address | https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28532087&ln= |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Data | Item |
|---|---|---|---|
 B2308511 | Certificate of Analysis | Nov 21, 2022 | C412338 |
| B2308513 | Certificate of Analysis | Nov 21, 2022 | C412338 |
| B2308521 | Certificate of Analysis | Nov 21, 2022 | C412338 |
| B2308522 | Certificate of Analysis | Nov 21, 2022 | C412338 |
| B2308523 | Certificate of Analysis | Nov 21, 2022 | C412338 |
| Solubilidade | Solubility (25°C) In vitro DMSO: 77 mg/mL (200.83 mM); Water: Insoluble; Ethanol: Insoluble; |
|---|---|
| Peso molecular | 383.400 g/mol |
| XLogP3 | 5.400 |
| Hydrogen Bond Donor Count | 1 |
| Hydrogen Bond Acceptor Count | 4 |
| Rotatable Bond Count | 3 |
| Exact Mass | 383.123 Da |
| Monoisotopic Mass | 383.123 Da |
| Topological Polar Surface Area | 41.600 Ų |
| Heavy Atom Count | 29 |
| Formal Charge | 0 |
| Complexity | 532.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 0 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
