CO23 - ≥98% , CAS No.1370363-74-8

CAS: 1370363-74-8 Cat. No.: C649591 Fórmula: C₁₉H₁₈I₂N₂O₄ Peso molecular: 592.17

GRADE & PURITY ≥98%

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrier

In Vivo

CO23 (ip; 0.04-5.0 nmol/g) has ≈50% cholesterol reduction with 0.8 nmol/g dose and higher doses are equally effective. CO23 has no effect at the lowest dose of 0.04 nmol/g and increases Dio1 mRNA 5-, 10-, and 15-fold at the doses of 0.8, 2.5, and 5 nmol/g, respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Hypothyroid Wistar rats Dosage: 0.04, 0.8, 2.5, and 5.0 nmol/g Administration: Ip Result: Had ≈50% cholesterol reduction with 0.8 nmol/g dose and higher doses were equally effective.

Form:Solid

IC50& Target:TRα

Specifications

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

CO23 is a selective thyroid hormone receptor (TR) α agonist and used for growth and development regulation. CO23 was able to be transported through the blood-brain barrier.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

AGONIST

Pureza

≥98%

Nomes e identificadores

• Peso molecular: 592.17

Propriedades químicas e físicas

• Solubilidade: DMSO : 250 mg/mL (422.18 mM; Need ultrasonic)