Coelenterazine 400 a - ≥95% , CAS No.70217-82-2

CAS: 70217-82-2 Cat. No.: C332017 Fórmula: C₂₆H₂₁N₃O Peso molecular: 391.46

GRADE & PURITY ≥95%

Synonyms

Coelenterazine 400 a is known as a bisdeoxy derivative of coelenterazine. | BlueSyn C | 2,8-dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3-ol | coelenterazine-400a | 2,8-dibenzyl-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one | AKOS030213259 | C-7010 | DTXSID10628592

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Visão geral

product description：

Coelenterazine 400 a is a chromophore that produces the chemiluminescence displayed by the Aequorin protein in the presence of Ca|2+|. Aequorin is employed as a chemiluminescent probe for intracellular Ca|2+|, and derivatives of this protein generated with various Coelenterazine derivatives produced a range of Ca|2+|probes with varying spectral properties. Coelenterazine 400 a is a bisdeoxy derivative of coelenterazine. Coelenterazine 400 a displays an emission maximum of 395nm following conversion by Renilla luciferase (Rluc). Coelenterazine 400 a is commonly paired with class 1 and 3 GFP acceptors.

Applications：

Coelenterazine 400 a is a blue emitting Rluc substrate for bioluminescence resonance energy transfer 2 (BRET2) studies.

Specifications

Sinónimos

Coelenterazine 400 a is known as a bisdeoxy derivative of coelenterazine. | BlueSyn C | 2,8-dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3-ol | coelenterazine-400a | 2,8-dibenzyl-6-phenyl-7H-imidazo[1,2-a]pyrazin-3-one | AKOS030213259 | C-7010 | DTXSID10628592

Especificações e pureza

≥95%

Condições de armazenamento de armazenamento

Protected from light,Store at -20°C,Argon charged

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Nota

Stock Solution1. Let the vial warm to room temperature before opening to prevent condensation from entering the product.2. Dissolve the product in ethanol at a concentration of 0.4 mg/ml. Mix gently.3. Avoid solvents such as DMSO as they may cause oxidati

Pureza

≥95%

Nomes e identificadores

Pubchem Sid

504773439

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504773439

Sorrisos canónicos

C1=CC=C(C=C1)CC2=C(N3C=C(N=C(C3=N2)CC4=CC=CC=C4)C5=CC=CC=C5)O

IUPAC Name

2,8-dibenzyl-6-phenylimidazo[1,2-a]pyrazin-3-ol

InChIKey

XNNYOKUWNAAJQW-UHFFFAOYSA-N

INCHI

1S/C26H21N3O/c30-26-23(17-20-12-6-2-7-13-20)28-25-22(16-19-10-4-1-5-11-19)27-24(18-29(25)26)21-14-8-3-9-15-21/h1-15,18,30H,16-17H2

SMILES isoméricas

C1=CC=C(C=C1)CC2=C(N3C=C(N=C(C3=N2)CC4=CC=CC=C4)C5=CC=CC=C5)O

Peso molecular

391.46

Reaxy-Rn

36019358

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=36019358&ln=

Propriedades químicas e físicas

• Solubilidade: Soluble in 0.1% warm acetone. Hardly soluble in water.
• Índice de refração: n20D1.66 (Predicted)
• Ponto de ebulição (°C): 551.39° C at 760 mmHg (Predicted)
• Ponto de fusão (°C): 94-98° C
• Peso molecular: 391.500 g/mol
• XLogP3: 6.200
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 391.168 Da
• Monoisotopic Mass: 391.168 Da
• Topological Polar Surface Area: 50.400 Ų
• Heavy Atom Count: 30
• Formal Charge: 0
• Complexity: 524.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1