CPI-1205 - Moligand™, ≥97% , Inhibitor of enhancer of zeste 2 polycomb repressive complex 2 subunit, CAS No.1621862-70-1, Inhibitor of enhancer of zeste 2 polycomb repressive complex 2 subunit

CAS: 1621862-70-1 Cat. No.: C174641 Fórmula: C27H33F3N4O3 Peso molecular: 518.581
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥97%
Synonyms
DB14581 | AC-35895 | N-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-2-methyl-1-[(1R)-1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]-1H-indole-3-carboxamide | A19399 | HPODOLXTMDHLLC-QGZVFWFLSA-N | 1450656-11-7 | 1621862-70-1 | CPI 1205 | L
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
Alemanha (EU)
USA*
Price
Qty
1mg
C174641-1mg
—
3 Em stock

91,03€

111,85€
Gravar 20,83 € (18.62%)
5mg
C174641-5mg
—
1 Em stock

299,28€

387,79€
Gravar 88,51 € (22.82%)
10mg
C174641-10mg
—
1 Em stock

529,23€

685,43€
Gravar 156,19 € (22.79%)
25mg
C174641-25mg
—
1 Em stock

1174,83€

1370,94€
Gravar 196,11 € (14.30%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

Moligand™, ≥97% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

CPI-1205 is a highly potent and selective inhibitor of EZH2(IC50 : 0.002 μM, EC50 : 0.032 μM) .

Specifications

Sinónimos
DB14581 | AC-35895 | N-[(4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-2-methyl-1-[(1R)-1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]-1H-indole-3-carboxamide | A19399 | HPODOLXTMDHLLC-QGZVFWFLSA-N | 1450656-11-7 | 1621862-70-1 | CPI 1205 | L
Especificações e pureza
Moligand™, ≥97%
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Grau
Moligand™
Tipo de ação
INHIBITOR
Mecanismo de ação
Inhibitor of enhancer of zeste 2 polycomb repressive complex 2 subunit
Pureza
≥97%
Nomes e identificadores
Pubchem Sid504772426
Pubchem Sid Urlhttps://pubchem.ncbi.nlm.nih.gov/substance/504772426
Sorrisos canónicosCC1=CC(=C(C(=O)N1)CNC(=O)C2=C(N(C3=CC=CC=C32)C(C)C4CCN(CC4)CC(F)(F)F)C)OC
IUPAC NameN-[(4-methoxy-6-methyl-2-oxo-1H-pyridin-3-yl)methyl]-2-methyl-1-[(1R)-1-[1-(2,2,2-trifluoroethyl)piperidin-4-yl]ethyl]indole-3-carboxamide
InChIKeyHPODOLXTMDHLLC-QGZVFWFLSA-N
INCHI1S/C27H33F3N4O3/c1-16-13-23(37-4)21(25(35)32-16)14-31-26(36)24-18(3)34(22-8-6-5-7-20(22)24)17(2)19-9-11-33(12-10-19)15-27(28,29)30/h5-8,13,17,19H,9-12,14-15H2,1-4H3,(H,31,36)(H,32,35)/t17-/m1/s1
SMILES isoméricas CC1=CC(=C(C(=O)N1)CNC(=O)C2=C(N(C3=CC=CC=C32)[C@H](C)C4CCN(CC4)CC(F)(F)F)C)OC
CAS alternativo 1450656-11-7,1621862-70-1
Termos de entrada MeSH (R)-N-((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1H-indole-3-carboxamide;CPI-1205
Peso molecular 518.581
Reaxy-Rn 24027186
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=24027186&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganoheterocyclic compounds
ClasseIndoles and derivatives
SubclassIndolecarboxylic acids and derivatives
Intermediate Tree Nodes Not available
Direct ParentIndolecarboxamides and derivatives
Alternative Parents N-alkylindoles  Indoles  Pyrrole carboxamides  Alkyl aryl ethers  Pyridinones  Dihydropyridines  Methylpyridines  Substituted pyrroles  Benzenoids  Piperidines  Heteroaromatic compounds  Vinylogous amides  Vinylogous esters  Trialkylamines  Amino acids and derivatives  Secondary carboxylic acid amides  Lactams  Azacyclic compounds  Alkyl fluorides  Organofluorides  Organic oxides  Hydrocarbon derivatives  
Molecular FrameworkAromatic heteropolycyclic compounds
Substituents Indolecarboxamide derivative - N-alkylindole - Indole - Pyrrole-3-carboxamide - Pyrrole-3-carboxylic acid or derivatives - Alkyl aryl ether - Dihydropyridine - Methylpyridine - Pyridinone - Hydropyridine - Piperidine - Pyridine - Substituted pyrrole - Benzenoid - Pyrrole - Vinylogous ester - Heteroaromatic compound - Vinylogous amide - Secondary carboxylic acid amide - Amino acid or derivatives - Tertiary aliphatic amine - Tertiary amine - Carboxamide group - Lactam - Azacycle - Carboxylic acid derivative - Ether - Alkyl halide - Organic oxide - Organic nitrogen compound - Hydrocarbon derivative - Organic oxygen compound - Organohalogen compound - Organofluoride - Amine - Organonitrogen compound - Organooxygen compound - Alkyl fluoride - Aromatic heteropolycyclic compound
DescriçãoThis compound belongs to the class of organic compounds known as indolecarboxamides and derivatives. These are compounds containing a carboxamide group attached to an indole.
External Descriptors Not available
Estrutura 3D
Modelo de Estrutura Química Interativa





Alvos associados (humanos)
EZH1 Tchem Histone-lysine N-methyltransferase EZH1 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
EZH2 Tclin Histone-lysine N-methyltransferase EZH2 (5 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
KCNH2 Tclin HERG (29587 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C8 Tchem Cytochrome P450 2C8 (1492 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EZH2 Tclin Histone-lysine N-methyltransferase EZH2 (2012 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
EZH1 Tchem Histone-lysine N-methyltransferase EZH1 (112 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
KARPAS-422 (454 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de ação
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDataItem
I2224142Certificate of AnalysisJul 10, 2025 C174641
I2224167Certificate of AnalysisJul 09, 2025 C174641
I2224145Certificate of AnalysisJul 09, 2025 C174641
C2514275Certificate of AnalysisAug 17, 2022 C174641
E2517055Certificate of AnalysisAug 17, 2022 C174641
I2224155Certificate of AnalysisAug 17, 2022 C174641
I2224156Certificate of AnalysisAug 17, 2022 C174641
L2404172Certificate of AnalysisAug 17, 2022 C174641
Propriedades químicas e físicas
Peso molecular518.600 g/mol
XLogP34.300
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count7
Rotatable Bond Count7
Exact Mass518.25 Da
Monoisotopic Mass518.25 Da
Topological Polar Surface Area75.600 Ų
Heavy Atom Count37
Formal Charge0
Complexity926.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
FAQs e artigos
Calculadoras de soluções
Revisões

Avaliações dos Clientes

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