Cyclosomatostatin - ≥97% , CAS No.84211-54-1

CAS: 84211-54-1(Free base) Cat. No.: C275432 Fórmula: C₄₆H₅₈F₃N₇O₈ Peso molecular: 893.99

GRADE & PURITY Moligand™, ≥97%

Synonyms

CPP1 | L-Threonine, N-(7-amino-1-oxoheptyl)-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))- | CyCam | Cyclo-(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[BZL]) | AKOS024457638 | Antagonist srif-A | Cyclo-(7-aminoheptano

Storage

Store at -20°C,Desiccated

Shipped In

Ice chest + Ice pads

Visão geral

Cyclosomatostatin TFA is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin (TFA) can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells.

Specifications

Sinónimos

CPP1 | L-Threonine, N-(7-amino-1-oxoheptyl)-L-phenylalanyl-D-tryptophyl-L-lysyl-O-(phenylmethyl)-, (2S-(1(R*(R*)),2alpha,3abeta,7abeta))- | CyCam | Cyclo-(7-aminoheptanoyl-Phe-D-Trp-Lys-Thr[BZL]) | AKOS024457638 | Antagonist srif-A | Cyclo-(7-aminoheptano

Especificações e pureza

Moligand™, ≥97%

Mecanismos bioquímicos e fisiológicos

Somatostatin antagonist with various biological activities. Blocks the effect of somatostatin on β-adrenergic function and CRF-induced suppression of gastric empyting, ACh release and growth hormone, insulin, and Glukagon release.

Condições de armazenamento de armazenamento

Store at -20°C,Desiccated

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Tipo de ação

ANTAGONIST

Nota

This product is supplied in one (or more) pack size which is freeze dried. Therefore the contents may not be readily visible, as they can coat the bottom or walls of the vial. Please see our FAQs and information page for more details on handling. Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥97%

Nomes e identificadores

• Sorrisos canónicos: CC(C1C(=O)NCCCCCCC(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=CC=C4)OCC5=CC=CC=C5
• IUPAC Name: (3S,6S,9R,12S)-6-(4-aminobutyl)-12-benzyl-9-(1H-indol-3-ylmethyl)-3-[(1R)-1-phenylmethoxyethyl]-1,4,7,10,13-pentazacycloicosane-2,5,8,11,14-pentone
• InChIKey: YHVHQZYJGWGAKN-ZUWUZHNASA-N
• INCHI: 1S/C44H57N7O6/c1-30(57-29-32-18-8-5-9-19-32)40-44(56)46-25-15-3-2-10-23-39(52)48-37(26-31-16-6-4-7-17-31)42(54)50-38(27-33-28-47-35-21-12-11-20-34(33)35)43(55)49-36(41(53)51-40)22-13-14-24-45/h4-9,11-12,16-21,28,30,36-38,40,47H,2-3,10,13-15,22-27,29,45H2,1H3,(H,46,56)(H,48,52)(H,49,55)(H,50,54)(H,51,53)/t30-,36+,37+,38-,40+/m1/s1
• Peso molecular: 893.99

Propriedades químicas e físicas

• Solubilidade: Soluble in DMSO to 1mg/ml
• Sensibilidade: Moisture sensitive
• Peso molecular: 780.000 g/mol
• XLogP3: 4.300
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 12
• Exact Mass: 779.437 Da
• Monoisotopic Mass: 779.437 Da
• Topological Polar Surface Area: 197.000 Ų
• Heavy Atom Count: 57
• Formal Charge: 0
• Complexity: 1270.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 5
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 84211-54-1, the molecular formula is C44H57N7O6, and the molecular weight is 779.97 g/mol. InChIKey YHVHQZYJGWGAKN-ZUWUZHNASA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.