D-erythro-sphingosine - Moligand™, ≥99% , Activator of TRPM3;Channel blocker of TRPM7, CAS No.123-78-4, Activator of TRPM3;Channel blocker of TRPM7

Name: D-erythro-sphingosine - Moligand™, ≥99% , Activator of TRPM3;Channel blocker of TRPM7, CAS No.123-78-4, Activator of TRPM3;Channel blocker of TRPM7
SKU: D130604
Availability: InStock

CAS: 123-78-4 Cat. No.: D130604 Fórmula: C₁₈H₃₇NO₂ Peso molecular: 299.492 Beilstein Registry Number: 1727294 Número CE: 204-651-3

2 Citations COA

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D-erythro-sphingosine - Moligand™, ≥99% CAS No(123-78-4) by Aladdin Scientific

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Disponível para encomenda

GRADE & PURITY Moligand™ ? ≥99%

Synonyms

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Specifications Nomes e identificadores Documentation Advanced Data Taxonomic Classification Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas FAQs e artigos Citations of This Product Calculadoras de soluções Revisões

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Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos

Especificações e pureza

Moligand™, ≥99%

Mecanismos bioquímicos e fisiológicos

Potent specific protein kinase C inhibitor. Naturally occurring long-chain amino diol. Active in vitro

Condições de armazenamento de armazenamento

Store at -20°C,Argon charged

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Tipo de ação

ACTIVATOR, CHANNEL BLOCKER

Mecanismo de ação

Activator of TRPM3;Channel blocker of TRPM7

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥99%

Nomes e identificadores

Pubchem Sid

528764071

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528764071

Sorrisos canónicos

CCCCCCCCCCCCCC=CC(C(CO)N)O

IUPAC Name

(E,2S,3R)-2-aminooctadec-4-ene-1,3-diol

InChIKey

WWUZIQQURGPMPG-KRWOKUGFSA-N

INCHI

1S/C18H37NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-18(21)17(19)16-20/h14-15,17-18,20-21H,2-13,16,19H2,1H3/b15-14+/t17-,18+/m0/s1

SMILES isoméricas

CCCCCCCCCCCCC/C=C/[C@H]([C@H](CO)N)O

WGK Alemanha

Peso molecular

299.492

Beilstein

1727294

Reaxy-Rn

8132315

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=8132315&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic nitrogen compounds
  - Classe Organonitrogen compounds
    - Subclass Amines
      - Level5 Alkanolamines
        Level6 1,2-aminoalcohols

Kingdom	Organic compounds
Superclass	Organic nitrogen compounds
Classe	Organonitrogen compounds
Subclass	Amines
Intermediate Tree Nodes	Alkanolamines
Direct Parent	1,2-aminoalcohols
Alternative Parents	Secondary alcohols Primary alcohols Organopnictogen compounds Monoalkylamines Hydrocarbon derivatives
Molecular Framework	Aliphatic acyclic compounds
Substituents	Secondary alcohol - 1,2-aminoalcohol - Organic oxygen compound - Organopnictogen compound - Hydrocarbon derivative - Primary amine - Primary alcohol - Organooxygen compound - Primary aliphatic amine - Alcohol - Aliphatic acyclic compound
Descrição	This compound belongs to the class of organic compounds known as 1,2-aminoalcohols. These are organic compounds containing an alkyl chain with an amine group bound to the C1 atom and an alcohol group bound to the C2 atom.
External Descriptors	Sphing-4-enines (Sphingosines)
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estrutura 3D

Alvos associados (humanos)

TRPM3 Tchem Transient receptor potential cation channel subfamily M member 3 (1 Activities)

Discover Target: TRPM3

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

TRPM7 Tchem Transient receptor potential cation channel subfamily M member 7 (1 Activities)

Discover Target: TRPM7

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

VDR Tclin Vitamin D receptor (26531 Activities)

Discover Target: VDR

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

THRB Tclin Thyroid hormone receptor beta-1 (7926 Activities)

Discover Target: THRB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

POLB Tchem DNA polymerase beta (23632 Activities)

Discover Target: POLB

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

CETP Tchem Cholesteryl ester transfer protein (2422 Activities)

Discover Target: CETP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GLA Tclin Alpha-galactosidase A (5444 Activities)

Discover Target: GLA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

GBA1 Tclin Beta-glucocerebrosidase (14647 Activities)

Discover Target: GBA1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SPHK2 Tchem Sphingosine kinase 2 (1579 Activities)

Discover Target: SPHK2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SMPD1 Tchem Sphingomyelin phosphodiesterase (13561 Activities)

Discover Target: SMPD1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

SPHK1 Tchem Sphingosine kinase 1 (1990 Activities)

Discover Target: SPHK1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

PRKACA Tchem cAMP-dependent protein kinase alpha-catalytic subunit (3475 Activities)

Discover Target: PRKACA

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

HepG2 (196354 Activities)

Lot Number	Certificate Type	Data	Item
H2309611	Certificate of Analysis	Aug 04, 2026	D130604
G2510245	Certificate of Analysis	Jun 11, 2025	D130604
G2510452	Certificate of Analysis	Jun 11, 2025	D130604
G2510453	Certificate of Analysis	Jun 11, 2025	D130604
G2510457	Certificate of Analysis	Jun 11, 2025	D130604
G2510458	Certificate of Analysis	Jun 11, 2025	D130604
H2211208	Certificate of Analysis	Feb 20, 2024	D130604
H2211213	Certificate of Analysis	Feb 20, 2024	D130604
H2211214	Certificate of Analysis	Feb 20, 2024	D130604
L2115168	Certificate of Analysis	Jun 14, 2023	D130604
L2115169	Certificate of Analysis	Jun 14, 2023	D130604
L2115170	Certificate of Analysis	Jun 14, 2023	D130604

Solubilidade	Slightly soluble in Chloroform
Sensibilidade	Air Sensitive,Heat Sensitive
Rotação específica [α]	-2° (C=1,CHCl3)
Ponto de fusão (°C)	74 °C
Peso molecular	299.500 g/mol
XLogP3	5.300
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	3
Rotatable Bond Count	15
Exact Mass	299.282 Da
Monoisotopic Mass	299.282 Da
Topological Polar Surface Area	66.500 Å²
Heavy Atom Count	21
Formal Charge	0
Complexity	231.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	2
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	1
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	1
Covalently-Bonded Unit Count	1

D-erythro-sphingosine - Moligand™, ≥99% , Activator of TRPM3;Channel blocker of TRPM7, CAS No.123-78-4, Activator of TRPM3;Channel blocker of TRPM7

Storage & shipping

Quality documents

Literature proof

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

Avaliações dos Clientes

📚 Citations by Application

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