Dapaconazole - 10mM in DMSO , CAS No.1269726-67-1

CAS: 1269726-67-1 Cat. No.: D655780 Fórmula: C₁₉H₁₅Cl₂F₃N₂O Peso molecular: 415.24 PubChem CID: 51001696

GRAU & PUREZA 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC 50 of 1.4 μM

In Vitro

Dapaconazole inhibits sterol 14α-demethylase cytochrome P450 activity with an IC 50 of 1.4 ± 0.3 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Dapaconazole (20 mg/kg; p.o.) shows that the bioavailability is 97.3 % . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male beagle dogs Dosage: 20 mg/kg (Pharmacokinetic Analysis) Administration: P.o. Result: Showed that the bioavailability was 97.3 %.

IC50& Target:CYP26 1.4 μM (IC 50 )

Especificações

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Dapaconazole, as an antifungal agent, inhibits sterol 14α-demethylase cytochrome P450 activity with an IC 50 of 1.4 μM.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Nomes e identificadores

SMILES isoméricas

C1=CC(=CC=C1COC(CN2C=CN=C2)C3=C(C=C(C=C3)Cl)Cl)C(F)(F)F

CAS alternativo

1269726-67-1

PubChem CID

51001696

Termos de entrada MeSH

1-(2-(2,4-dichlorophenyl)-2-(4-(trifluoromethyl)benzyloxy)ethyl)-1H-imidazole;dapaconazole

Peso molecular

415.24