Daptomycin - Moligand™, ≥98% , CAS No.103060-53-3

Name: Daptomycin - Moligand™, ≥98% , CAS No.103060-53-3
Brand: Aladdin Scientific
SKU: D129529
Availability: InStock

CAS: 103060-53-3 Cat. No.: D129529 Fórmula: C₇₂H₁₀₁N₁₇O₂₆ Peso molecular: 1620.67 Número CE: 600-389-2 PubChem CID: 16134395

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Daptomycin - Moligand™, ≥98% CAS No(103060-53-3) D129529 by Aladdin Scientific

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Disponível para encomenda

GRAU & PUREZA Moligand™ ? ≥98%

Synonyms

N-decanoyl-L-tryptophyl-L-asparaginyl-N-[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-ox|(3S)-3-{[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-Aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonaa|N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine epsilon(1)-lactone|(2S)-daptomycin|LY 146032|Cubicin|N-decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine 1.13-3.4-lactone|DAPTOMYCIN|LY146032

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Folha de especificações

Visão geral Especificações Propriedades do produto Nomes e identificadores Dados avançados Taxonomic Classification Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Citations of This Product Calculadoras de soluções Revisões

Visão geral

Daptomycin is a lipopeptide antibiotic with rapid in vitro bactericidal activity against gram-positive organisms.

Especificações

Sinónimos

Especificações e pureza

Moligand™, ≥98%

Mecanismos bioquímicos e fisiológicos

Daptomycin is a lipopeptide antibiotic produced by Streptomyces roseosporus with reported in vitro bactericidal activity against gram-positive organisms. As a calcium-dependent antibiotic, Daptomycin has been reported to act on the cytoplasmic membrane an

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Propriedades do produto

ALogP

-5.1

Nomes e identificadores

Pubchem Sid

504768064

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504768064

Sorrisos canónicos

CCCCCCCCCC(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC(=O)N)C(=O)NC(CC(=O)O)C(=O)NC3C(OC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)CNC3=O)CCCN)CC(=O)O)C)CC(=O)O)CO)C(C)CC(=O)O)CC(=O)C4=CC=CC=C4N)C

IUPAC Name

(3S)-3-[[(2S)-4-amino-2-[[(2S)-2-(decanoylamino)-3-(1H-indol-3-yl)propanoyl]amino]-4-oxobutanoyl]amino]-4-[[(3S,6S,9R,15S,18R,21S,24S,30S,31R)-3-[2-(2-aminophenyl)-2-oxoethyl]-24-(3-aminopropyl)-15,21-bis(carboxymethyl)-6-[(2R)-1-carboxypropan-2-yl]-9-(hydroxymethyl)-18,31-dimethyl-2,5,8,11,14,17,20,23,26,29-decaoxo-1-oxa-4,7,10,13,16,19,22,25,28-nonazacyclohentriacont-30-yl]amino]-4-oxobutanoic acid

InChIKey

DOAKLVKFURWEDJ-RWDRXURGSA-N

INCHI

1S/C72H101N17O26/c1-5-6-7-8-9-10-11-22-53(93)81-44(25-38-31-76-42-20-15-13-17-39(38)42)66(108)84-45(27-52(75)92)67(109)86-48(30-59(102)103)68(110)89-61-37(4)115-72(114)49(26-51(91)40-18-12-14-19-41(40)74)87-71(113)60(35(2)24-56(96)97)88-69(111)50(34-90)82-55(95)32-77-63(105)46(28-57(98)99)83-62(104)36(3)79-65(107)47(29-58(100)101)85-64(106)43(21-16-23-73)80-54(94)33-78-70(61)112/h12-15,17-20,31,35-37,43-50,60-61,76,90H,5-11,16,21-30,32-34,73-74H2,1-4H3,(H2,75,92)(H,77,105)(H,78,112)(H,79,107)(H,80,94)(H,81,93)(H,82,95)(H,83,104)(H,84,108)(H,85,106)(H,86,109)(H,87,113)(H,88,111)(H,89,110)(H,96,97)(H,98,99)(H,100,101)(H,102,103)/t35-,36-,37-,43+,44+,45+,46+,47+,48+,49+,50-,60+,61+/m1/s1

SMILES isoméricas

CCCCCCCCCC(=O)N[C@@H](CC1=CNC2=CC=CC=C21)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@H]3[C@H](OC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)CNC3=O)CCCN)CC(=O)O)C)CC(=O)O)CO)[C@H](C)CC(=O)O)CC(=O)C4=CC=CC=C4N)C

PubChem CID

16134395

Peso molecular

1620.67

Dados avançados

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Classe Peptidomimetics
    - Subclass Depsipeptides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Classe	Peptidomimetics
Subclass	Depsipeptides
Intermediate Tree Nodes	Not available
Direct Parent	Cyclic depsipeptides
Alternative Parents	Pentacarboxylic acids and derivatives Alkyl-phenylketones Alpha amino acid esters Macrolides and analogues Macrolactams 3-alkylindoles Aniline and substituted anilines Aryl alkyl ketones Benzoyl derivatives Substituted pyrroles Vinylogous amides Heteroaromatic compounds Cyclic carboximidic acids Amino acids Lactones Carboxylic acid esters Propargyl-type 1,3-dipolar organic compounds Polyols Oxacyclic compounds Azacyclic compounds Carboxylic acids Organic oxides Primary alcohols Monoalkylamines Hydrocarbon derivatives Organopnictogen compounds
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Cyclic depsipeptide - Pentacarboxylic acid or derivatives - Alpha-amino acid ester - Alkyl-phenylketone - Macrolide - Macrolactam - Alpha-amino acid or derivatives - 3-alkylindole - Phenylketone - Indole - Indole or derivatives - Aniline or substituted anilines - Aryl alkyl ketone - Aryl ketone - Benzoyl - Substituted pyrrole - Monocyclic benzene moiety - Benzenoid - Vinylogous amide - Cyclic carboximidic acid - Pyrrole - Heteroaromatic compound - Amino acid or derivatives - Carboxylic acid ester - Amino acid - Ketone - Lactone - Propargyl-type 1,3-dipolar organic compound - Polyol - Organic 1,3-dipolar compound - Organoheterocyclic compound - Azacycle - Carboximidic acid - Carboximidic acid derivative - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Organooxygen compound - Organic oxygen compound - Organic nitrogen compound - Hydrocarbon derivative - Amine - Alcohol - Carbonyl group - Organic oxide - Organopnictogen compound - Primary aliphatic amine - Organonitrogen compound - Primary alcohol - Primary amine - Aromatic heteropolycyclic compound
Descrição	This compound belongs to the class of organic compounds known as cyclic depsipeptides. These are natural or synthetic compounds having sequences of amino and hydroxy carboxylic acid residues (usually α-amino and α-hydroxy acids) connected in a ring. The residues are commonly but not necessarily regularly alternating.
External Descriptors	lipopeptide - heterodetic cyclic peptide - macrolide - macrocycle - lipopeptide antibiotic
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

Homo sapiens (32628 Activities)

Lot Number	Certificate Type	Data	Item
C2406146	Certificate of Analysis	Dec 12, 2025	D129529
C2406147	Certificate of Analysis	Dec 12, 2025	D129529
C2218481	Certificate of Analysis	Oct 11, 2025	D129529
C2218482	Certificate of Analysis	Oct 11, 2025	D129529
C2218639	Certificate of Analysis	Oct 11, 2025	D129529
D2627069	Certificate of Analysis	Jul 16, 2025	D129529
I2610147	Certificate of Analysis	Jul 16, 2025	D129529
H2525266	Certificate of Analysis	Jul 16, 2025	D129529
H2525267	Certificate of Analysis	Jul 16, 2025	D129529
H2525273	Certificate of Analysis	Jul 16, 2025	D129529
I2603156	Certificate of Analysis	Jul 16, 2025	D129529
J2311281	Certificate of Analysis	Jul 10, 2025	D129529
J2311279	Certificate of Analysis	Jul 10, 2025	D129529
J2311278	Certificate of Analysis	Jul 10, 2025	D129529
J2311277	Certificate of Analysis	Jul 10, 2025	D129529
H2310103	Certificate of Analysis	May 12, 2025	D129529
G2320189	Certificate of Analysis	May 12, 2025	D129529
C2406145	Certificate of Analysis	Feb 20, 2024	D129529
J2311280	Certificate of Analysis	Sep 21, 2023	D129529
J2311282	Certificate of Analysis	Sep 21, 2023	D129529
B2301912	Certificate of Analysis	Feb 22, 2022	D129529
C2218484	Certificate of Analysis	Feb 22, 2022	D129529
C2218483	Certificate of Analysis	Feb 22, 2022	D129529

Solubilidade	Soluble in water (100 mg/ml at 25 °C), ethanol (50 mM), methanol (5 mg/ml), DMSO (100 mM), and DMF.
Sensibilidade	Heat sensitive
Peso molecular	1620.700 g/mol
XLogP3	-5.100
Hydrogen Bond Donor Count	22
Hydrogen Bond Acceptor Count	28
Rotatable Bond Count	35
Exact Mass	1619.71 Da
Monoisotopic Mass	1619.71 Da
Topological Polar Surface Area	702.000 Å²
Heavy Atom Count	115
Formal Charge	0
Complexity	3480.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	13
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Daptomycin - Moligand™, ≥98% , CAS No.103060-53-3

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