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Início
Ciência dos Materiais
Materiais biomédicos
Polietilenoglicol (PEGs e PEOs)
DBCO-PEG1-NHS ester - ≥98% , CAS No.2228857-34-7

DBCO-PEG1-NHS ester - ≥98% , CAS No.2228857-34-7

Name: DBCO-PEG1-NHS ester - ≥98% , CAS No.2228857-34-7
SKU: D596699
Availability: InStock

CAS: 2228857-34-7 Cat. No.: D596699 Fórmula: C₂₈H₂₇N₃O₇ Peso molecular: 517.53

COA

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DBCO-PEG1-NHS ester - ≥98% CAS No(2228857-34-7) D596699 by Aladdin Scientific

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Disponível para encomenda

GRADE & PURITY ≥98%

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Application

Antibody Drug Conjugates(ADC), Drug Delivery, Surface Modification, PEGylation of Protein, Peptide & Oligo

Visão geral Specifications Nomes e identificadores Documentation Advanced Data Estrutura 3D Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas FAQs e artigos Calculadoras de soluções Revisões

🧪

Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Protected from light,Store at -20°C,Argon charged Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

DBCO-PEG1-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. DBCO-PEG1-NHS ester is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.

Specifications

Especificações e pureza

≥98%

Condições de armazenamento de armazenamento

Protected from light,Store at -20°C,Argon charged

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥98%

Nomes e identificadores

Pubchem Sid

528764098

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528764098

Sorrisos canónicos

C1CC(=O)N(C1=O)OC(=O)CCOCCNC(=O)CCC(=O)N2CC3=CC=CC=C3C#CC4=CC=CC=C42

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 3-[2-[[4-(2-azatricyclo[10.4.0.04,9]hexadeca-1(16),4,6,8,12,14-hexaen-10-yn-2-yl)-4-oxobutanoyl]amino]ethoxy]propanoate

InChIKey

TYDZSBPFYBWRTP-UHFFFAOYSA-N

INCHI

1S/C28H27N3O7/c32-24(29-16-18-37-17-15-28(36)38-31-26(34)13-14-27(31)35)11-12-25(33)30-19-22-7-2-1-5-20(22)9-10-21-6-3-4-8-23(21)30/h1-8H,11-19H2,(H,29,32)

Peso molecular

517.53

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estrutura 3D

Certificados（CoA,COO,BSE/TSE e Mapa de Análise)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

3 results found

Lot Number	Certificate Type	Data	Item
I2523343	Certificate of Analysis	Jul 18, 2025	D596699
I2523344	Certificate of Analysis	Jul 18, 2025	D596699
I2523345	Certificate of Analysis	Jul 18, 2025	D596699

Propriedades químicas e físicas

Solubilidade	Solubility in DMSO, DCM, DMF
Sensibilidade	Light sensitive；Moisture sensitive
Peso molecular	517.500 g/mol
XLogP3	0.800
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	11
Exact Mass	517.185 Da
Monoisotopic Mass	517.185 Da
Topological Polar Surface Area	122.000 Å²
Heavy Atom Count	38
Formal Charge	0
Complexity	967.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

FAQs e artigos

Polyethylene Glycol (PEG) and Its Derivatives: End-Group Design and Applications in PROTACs, ADCs, and Medical Device

Categories: Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Tags:

Polyethylene Glycol (PEG) PEGylation

Calculadoras de soluções

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Revisões

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