Diacetoxiscirpenol - ≥97%(HPLC) , CAS No.2270-40-8

Name: Diacetoxiscirpenol - ≥97%(HPLC) , CAS No.2270-40-8
SKU: D137912
Availability: InStock

CAS: 2270-40-8 Cat. No.: D137912 Fórmula: C₁₉H₂₆O₇ Peso molecular: 366.41 Número CE: 218-873-3

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Diacetoxiscirpenol - ≥97%(HPLC) CAS No(2270-40-8) by Aladdin Scientific

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Disponível para encomenda

GRADE & PURITY ≥97%(HPLC)

Synonyms

Storage

Armazenar a -20°C

Shipped In

Arca de gelo + almofadas de gelo

Visão geral Specifications Nomes e identificadores Documentation Advanced Data Taxonomic Classification Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Citations of This Product Calculadoras de soluções Revisões

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Why this grade

≥97%(HPLC) for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Armazenar a -20°C Ships Arca de gelo + almofadas de gelo Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 2 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

O diacetoxiscirpenol é uma micotoxina pertencente ao grupo dos 12,13-epoxitricotecenos, produzida por várias estirpes de Fusarium juntamente com algumas outras toxinas, como as toxinas T2 e HT2. Provoca toxicose fusarium em animais de criação.
O diacetoxiscirpenol (anguidina) e os seus derivados possuem propriedades anticancerígenas. O diacetoxiscirpenol (anguidina) inibe o início da síntese proteica, provocando a morte de células em rápida proliferação. O diacetoxiscirpenol (anguidina) também demonstrou potenciar e proteger contra os efeitos citotóxicos de outros medicamentos. Foram registados 14 ensaios clínicos, todos na área dos tumores colorrectais e da leucemia. Não foram encontrados registos após 1985. Indução de apoptose.

Specifications

Sinónimos

Especificações e pureza

≥97%(HPLC)

Condições de armazenamento de armazenamento

Armazenar a -20°C

Enviado em

Arca de gelo + almofadas de gelo

Pureza

≥97%(HPLC)

Nomes e identificadores

Pubchem Sid

528775611

Sorrisos canónicos

CC1=CC2C(CC1)(C3(C(C(C(C34CO4)O2)O)OC(=O)C)C)COC(=O)C

IUPAC Name

[(1S,2R,7R,9R,10R,11S,12S)-11-acetyloxy-10-hydroxy-1,5-dimethylspiro[8-oxatricyclo[7.2.1.02,7]dodec-5-ene-12,2'-oxirane]-2-yl]methyl acetate

InChIKey

AUGQEEXBDZWUJY-NMAPUUFXSA-N

INCHI

1S/C19H26O7/c1-10-5-6-18(8-23-11(2)20)13(7-10)26-16-14(22)15(25-12(3)21)17(18,4)19(16)9-24-19/h7,13-16,22H,5-6,8-9H2,1-4H3/t13-,14-,15-,16-,17-,18-,19+/m1/s1

SMILES isoméricas

CC1=C[C@@H]2[C@](CC1)([C@]3([C@@H]([C@H]([C@H]([C@@]34CO4)O2)O)OC(=O)C)C)COC(=O)C

WGK Alemanha

Peso molecular

366.41

Reaxy-Rn

38538014

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=38538014&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Lipids and lipid-like molecules
  - Classe Prenol lipids
    - Subclass Sesquiterpenoids

Kingdom	Organic compounds
Superclass	Lipids and lipid-like molecules
Classe	Prenol lipids
Subclass	Sesquiterpenoids
Intermediate Tree Nodes	Not available
Direct Parent	Trichothecenes
Alternative Parents	Oxepanes Oxanes Dicarboxylic acids and derivatives Secondary alcohols Cyclic alcohols and derivatives Carboxylic acid esters Oxacyclic compounds Epoxides Dialkyl ethers Organic oxides Hydrocarbon derivatives Carbonyl compounds
Molecular Framework	Aliphatic heteropolycyclic compounds
Substituents	Trichothecene skeleton - Oxepane - Dicarboxylic acid or derivatives - Oxane - Cyclic alcohol - Carboxylic acid ester - Secondary alcohol - Carboxylic acid derivative - Dialkyl ether - Oxirane - Ether - Oxacycle - Organoheterocyclic compound - Hydrocarbon derivative - Carbonyl group - Alcohol - Organooxygen compound - Organic oxygen compound - Organic oxide - Aliphatic heteropolycyclic compound
Descrição	This compound belongs to the class of organic compounds known as trichothecenes. These are sesquiterpene mycotoxins structurally characterized by the presence of an epoxide ring and a benzopyran derivative with a variant number of hydroxyl, acetyl, or other substituents. The most important structural features causing the biological activities of trichothecenes are the 12,13-epoxy ring, the presence of hydroxyl or acetyl groups at appropriate positions on the trichothecene nucleus and the structure and position of the side-chain.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estrutura 3D

Alvos associados (humanos)

XBP1 Tchem X-box-binding protein 1 (1 Activities)

Discover Target: XBP1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

ACHE Tclin Acetylcholinesterase (18204 Activities)

Discover Target: ACHE

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

TP53 Tchem Cellular tumor antigen p53 (48468 Activities)

Discover Target: TP53

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	Data	Item
I2525092	Certificate of Analysis	Oct 11, 2025	D137912
L2327080	Certificate of Analysis	Jan 03, 2024	D137912
L2321441	Certificate of Analysis	Jan 03, 2024	D137912
H1828087	Certificate of Analysis	Jun 24, 2022	D137912
H1828086	Certificate of Analysis	Jun 24, 2022	D137912

Solubilidade	Soluble in moderately polar solvents, such as chloroform, diethyl ether, ethyl acetate, and acetone
Sensibilidade	light sensitive
Ponto de inflamação (°F)	5°C
Ponto de inflamação (°C)	5°C
Ponto de fusão (°C)	160°C- 164°C
Peso molecular	366.400 g/mol
XLogP3	0.200
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	5
Exact Mass	366.168 Da
Monoisotopic Mass	366.168 Da
Topological Polar Surface Area	94.600 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	687.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	7
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

Diacetoxiscirpenol - ≥97%(HPLC) , CAS No.2270-40-8

Storage & shipping

Quality documents

Literature proof

Visão geral

Specifications

Documentation

📋 Safety Data Sheet (SDS)

✅ Certificate of Analysis (COA)

📊 Datasheet

🔬 Specification Sheet

Advanced Data

Molarity Calculator

Dilution Calculator

Reconstitution Calculator

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