Diisopropylcarbodiimide solution - 1 M in dichloromethane , CAS No.693-13-0

CAS: 693-13-0 Cat. No.: D433331 Fórmula: C₇H₁₄N₂ Peso molecular: 126.20 Beilstein Registry Number: 878281 Número CE: 211-743-7

GRAU & PUREZA 1 M in dichloromethane

Synonyms

EINECS 211-743-7 | diisopropyl carbodiimide | N,N'-Diisopropyl carbodimide | dipropan-2-ylmethanediimine | N-((isopropylimino)methyl-ene)propan-2-amine | N-((isopropylimino)methylene)propan-2-amine | STR04127 | UNII-OQO20I6TWH | DIC, 99% | MFCD00065689 |

Storage

Room temperature

Visão geral

General Description

DIC is an abbreviated form of N , N ′-diisopropylcarbodiimide. It plays a role in the cyclization of N -(β-hydroxy)amides to form 2-oxazolines.

Application

Valuable reagent offered as a solution in dichloromethane for more convenient handling. Alternative to dicyclohexylcarbodiimide in peptide synthesis. Coupling reagent for peptide syntheses. DIC ( N , N′ -Diisopropylcarbodiimide) has been used in combination with 1-hydroxy-7-azabenzotriazole (HOAt) for the coupling of amino acid with N -allylglycine to form N -allylpeptide.

Especificações

Sinónimos

EINECS 211-743-7 | diisopropyl carbodiimide | N,N'-Diisopropyl carbodimide | dipropan-2-ylmethanediimine | N-((isopropylimino)methyl-ene)propan-2-amine | N-((isopropylimino)methylene)propan-2-amine | STR04127 | UNII-OQO20I6TWH | DIC, 99% | MFCD00065689 |

Especificações e pureza

1 M in dichloromethane

Condições de armazenamento de armazenamento

Room temperature

Nomes e identificadores

Sorrisos canónicos

CC(C)N=C=NC(C)C

InChIKey

BDNKZNFMNDZQMI-UHFFFAOYSA-N

INCHI

1S/C7H14N2/c1-6(2)8-5-9-7(3)4/h6-7H,1-4H3

SMILES isoméricas

CC(C)N=C=NC(C)C

WGK Alemanha

3

RTECS

FF2175000

Número UN

2929

Peso molecular

126.20

Beilstein

878281

Reaxy-Rn

878281

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=878281&ln=

Alvos associados (humanos)

KCNH2 Tclin HERG (29587 Activities)

Discover Target: KCNH2

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Índice de refração: 1.433
• Ponto de inflamação (°F): 91°F
• Ponto de inflamação (°C): 31°C
• Ponto de ebulição (°C): 145-148°C
• Peso molecular: 126.200 g/mol
• XLogP3: 2.600
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 126.116 Da
• Monoisotopic Mass: 126.116 Da
• Topological Polar Surface Area: 24.700 Ų
• Heavy Atom Count: 9
• Formal Charge: 0
• Complexity: 101.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1