DX600 TFA - ≥99% , CAS No.D414451

CAS: D414451 Cat. No.: D414451 Fórmula: C141H185N35O40S2 Peso molecular: 3074.32
Disponível para encomenda
GRADE & PURITY ≥99%
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
★
Size
Alemanha (EU)
USA*
Price
Qty
1mg
D414451-1mg
—
6 Em stock

248,09€

289,74€
Gravar 41,65 € (14.38%)
5mg
D414451-5mg
—
7 Em stock
867,65€
25mg
D414451-25mg
—
5 Em stock

2479,91€

2892,96€
Gravar 413,04 € (14.28%)
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Information

DX600 DX600 is a specific inhibitor of angiotensin-converting enzyme 2 (ACE2) that does not cross-react with ACE.


Targets

ACE2


In vitro

DX600 is an ACE2 specific inhibitor that does not cross-react with ACE. Three human cell lines (Calu-3, Caco-2, Huh-7) are evaluated for the cell surface expression of ACE2 by flow cytometry and Western blot. Subsequently, whole cell lysates, cell culture supernatant, and live cells are evaluated in the assay. Calu-3 has elevated levels of ACE2 compared to Caco-2 or Huh-7. Calu-3 also demonstrates elevated ACE2 enzymatic activity in all three sources and can be inhibited by DX600.


In vivo

Mouse ACE2-driven Ang-(1-7) formation from Ang II is blocked by MLN-4760 but not by either linear or cyclic DX600. DX600 only blocks human ACE2 activity.


Cell Research(from reference)

Cell lines:Three human cell lines (Calu-3, Caco-2, Huh-7) 

Concentrations:10 μM 

Incubation Time:1 h 

Specifications

Especificações e pureza
≥99%
Mecanismos bioquímicos e fisiológicos
DX600 is a specific inhibitor of angiotensin-converting enzyme 2 (ACE2) that does not cross-react with ACE.
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Tipo de ação
INHIBITOR
Pureza
≥99%
Nomes e identificadores
Peso molecular 3074.32

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDataItem
G2313477Certificate of AnalysisApr 07, 2026 D414451
G2313479Certificate of AnalysisApr 07, 2026 D414451
G2313487Certificate of AnalysisApr 07, 2026 D414451
G2313488Certificate of AnalysisApr 07, 2026 D414451
G2313493Certificate of AnalysisApr 07, 2026 D414451
G2313514Certificate of AnalysisApr 07, 2026 D414451
Propriedades químicas e físicas
SolubilidadeSolubility (25°C) In vitro Water: 100 mg/mL (32.52 mM);    
Calculadoras de soluções
Revisões

Avaliações dos Clientes

Shall we send you a message when we have discounts available?

Remind me later

Thank you! Please check your email inbox to confirm.

Oops! Notifications are disabled.