Dyclonine HCl - 10mM in DMSO , Sodium channel alpha subunit blocker, CAS No.536-43-6, Sodium channel alpha subunit blocker

CAS: 536-43-6 Cat. No.: D409239 Fórmula: C₁₈H₂₇NO₂ · HCl Peso molecular: 325.87 Número CE: 208-633-6

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

1-​(4-​butoxyphenyl)​-​3-​(1-​piperidinyl)​-1-​propanone,hydrochloride (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Information

Dyclonine HCl Dyclonine HCl is a hydrochloride salt form of dyclonine which is an oral anaesthetic, reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane's permeability to sodium ions, leading t
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

1-​(4-​butoxyphenyl)​-​3-​(1-​piperidinyl)​-1-​propanone,hydrochloride (1:1)

Especificações e pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Dyclonine HCl is a hydrochloride salt form of dyclonine which is an oral anaesthetic, reversibly binds to activated sodium channels on the neuronal membrane, thereby decreasing the neuronal membrane\'s permeability to sodium ions, leading to an increased

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Tipo de ação

BLOCKER

Mecanismo de ação

Sodium channel alpha subunit blocker

Nomes e identificadores

• SMILES isoméricas: CCCCOC1=CC=C(C=C1)C(=O)CCN2CCCCC2.Cl
• WGK Alemanha: 3
• RTECS: UG8750000
• Peso molecular: 325.87
• Reaxy-Rn: 3744808
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3744808&ln=

Propriedades químicas e físicas

• Ponto de fusão (°C): 175-176°C

Referências

1. Xiaokang Guan, Qiao Lu, Xiangxu Zhao, Xiaowen Yan, Renato Zenobi.  (2023)  Spatio-Temporal Analysis of Anesthetics in Mice by Solid-Phase Microextraction: Dielectric Barrier Discharge Ionization Mass Spectrometry.  ANALYTICAL CHEMISTRY,      [PMID:37560898] [10.1021/acs.analchem.3c02123]

2. Wen-Jing Li, Li-Ying Wen, Yu-Sang Li, He-Bin Tang.  (2026)  Topical Application of Frankincense Oil Extract Potently Ameliorates Psoriasis-like Dermatitis in Mice via Anti-Inflammatory and Skin Barrier-Protective Effects.  INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,  27  (6):   [PMID:41898492] [10.3390/ijms27062629]