Equinomicina - ≥98% , CAS No.512-64-1

Name: Equinomicina - ≥98% , CAS No.512-64-1
SKU: E275307
Availability: InStock

CAS: 512-64-1 Cat. No.: E275307 Fórmula: C₅₁H₆₄N₁₂O₁₂S₂ Peso molecular: 1101.26 Número CE: 637-095-9

COA

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Equinomicina - ≥98% CAS No(512-64-1) by Aladdin Scientific

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Disponível para encomenda

GRADE & PURITY ≥98%

Synonyms

C 6388 | GNF-PF-1958 | equinomicina (estereoquímica indefinida) | N,N'-(11,24-diisopropil-2,4,12,15,17,25-hexametil-27-(metiltio)-3,6,10,13,16,19,23,26-octaoxo-9,22-dioxa-28-tia-2,5,12,15,18,25-hexaazabiciclo[12.12.3]nonacosano-7,20-diil)bis(quinoxalina

Storage

Armazenar a -20°C, carregado com árgon, dessecado

Shipped In

Arca de gelo + almofadas de gelo

Visão geral Specifications Nomes e identificadores Documentation Advanced Data Taxonomic Classification Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Calculadoras de soluções Revisões

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Why this grade

≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Armazenar a -20°C, carregado com árgon, dessecado Ships Arca de gelo + almofadas de gelo Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Descrição do produto:

Antibiótico ； Composto antitumoral ； Inibidor poderoso e seletivo da síntese de ácido nucleico in vitro ； Potente inibidor da atividade de ligação ao DNA do fator induzível por hipóxia 1 (HIF-1) ； Indutor de apoptose ； Antibacteriano, antifúngico e antiviral；Mostrado para inibir a via IFN-MHC classe I tipo I em células precursoras musculares (mioblastos).

Specifications

Sinónimos

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

Inibidor potente e reversível do HIF-1α permeável às células (EC 50 = 1,2 nM, atividade de transcrição do HIF-1 induzida por hipoxia em células U215). Intercala-se especificamente no ADN. Efeitos antibacterianos, antivirais, antiangiogénicos e antitumorai

Condições de armazenamento de armazenamento

Armazenar a -20°C, carregado com árgon, dessecado

Enviado em

Arca de gelo + almofadas de gelo

Tipo de ação

INHIBITOR

Nota

Sempre que possível, deve preparar e utilizar as soluções no mesmo dia. No entanto, se precisar de preparar soluções de reserva com antecedência, recomendamos que guarde a solução como alíquotas em frascos hermeticamente fechados a -20°C. Em geral, estas podem ser utilizadas durante uma semana. Antes de utilizar, e antes de abrir o frasco para injectáveis, recomendamos que deixe o seu produto equilibrar à temperatura ambiente durante pelo menos 1 hora. Precisa de mais conselhos sobre solubilidade, utilização e manuseamento? Para mais informações, visite a nossa página de perguntas frequentes (FAQ).

Pureza

≥98%

Nomes e identificadores

Sorrisos canónicos	CC1C(=O)N(C2CSC(C(C(=O)N(C(C(=O)OCC(C(=O)N1)NC(=O)C3=NC4=CC=CC=C4N=C3)C(C)C)C)N(C(=O)C(NC(=O)C(COC(=O)C(N(C2=O)C)C(C)C)NC(=O)C5=NC6=CC=CC=C6N=C5)C)C)SC)C
IUPAC Name	N-[2,4,12,15,17,25-hexamethyl-27-methylsulfanyl-3,6,10,13,16,19,23,26-octaoxo-11,24-di(propan-2-yl)-20-(quinoxaline-2-carbonylamino)-9,22-dioxa-28-thia-2,5,12,15,18,25-hexazabicyclo[12.12.3]nonacosan-7-yl]quinoxaline-2-carboxamide
InChIKey	AUJXLBOHYWTPFV-UHFFFAOYSA-N
INCHI	1S/C51H64N12O12S2/c1-25(2)38-49(72)74-22-36(59-42(65)34-21-53-30-17-13-15-19-32(30)57-34)44(67)55-28(6)46(69)63(10)40-48(71)62(9)39(26(3)4)50(73)75-23-35(58-41(64)33-20-52-29-16-12-14-18-31(29)56-33)43(66)54-27(5)45(68)60(7)37(47(70)61(38)8)24-77-51(40)76-11/h12-21,25-28,35-40,51H,22-24H2,1-11H3,(H,54,66)(H,55,67)(H,58,64)(H,59,65)
SMILES isoméricas	CC1C(=O)N(C2CSC(C(C(=O)N(C(C(=O)OCC(C(=O)N1)NC(=O)C3=NC4=CC=CC=C4N=C3)C(C)C)C)N(C(=O)C(NC(=O)C(COC(=O)C(N(C2=O)C)C(C)C)NC(=O)C5=NC6=CC=CC=C6N=C5)C)C)SC)C
Peso molecular	1101.26
Reaxy-Rn	1071158
Reaxys-RN_link_address	https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1071158&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organic acids and derivatives
  - Classe Peptidomimetics
    - Subclass Depsipeptides

Kingdom	Organic compounds
Superclass	Organic acids and derivatives
Classe	Peptidomimetics
Subclass	Depsipeptides
Intermediate Tree Nodes	Not available
Direct Parent	Cyclic depsipeptides
Alternative Parents	Macrolide lactams Alpha amino acid esters N-acyl-alpha amino acids and derivatives Macrolactams Quinoxalines Pyrazinecarboxamides 2-heteroaryl carboxamides Benzenoids Dicarboxylic acids and derivatives Tertiary carboxylic acid amides Dithioacetals Heteroaromatic compounds Secondary carboxylic acid amides Carboxylic acid esters Lactones Lactams Sulfenyl compounds Oxacyclic compounds Azacyclic compounds Dialkylthioethers Carbonyl compounds Organonitrogen compounds Organopnictogen compounds Organic oxides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Cyclic depsipeptide - Macrolide lactam - Alpha-amino acid ester - Macrolactam - N-acyl-alpha amino acid or derivatives - Diazanaphthalene - Alpha-amino acid or derivatives - Quinoxaline - Pyrazine carboxylic acid or derivatives - Pyrazinecarboxamide - 2-heteroaryl carboxamide - Dicarboxylic acid or derivatives - Pyrazine - Benzenoid - Thioacetal - Heteroaromatic compound - Tertiary carboxylic acid amide - Secondary carboxylic acid amide - Carboxamide group - Carboxylic acid ester - Lactam - Lactone - Thioether - Sulfenyl compound - Dialkylthioether - Carboxylic acid derivative - Organoheterocyclic compound - Azacycle - Oxacycle - Organic nitrogen compound - Organic oxide - Organopnictogen compound - Carbonyl group - Organosulfur compound - Hydrocarbon derivative - Organic oxygen compound - Organonitrogen compound - Organooxygen compound - Aromatic heteropolycyclic compound
Descrição	This compound belongs to the class of organic compounds known as cyclic depsipeptides. These are natural or synthetic compounds having sequences of amino and hydroxy carboxylic acid residues (usually α-amino and α-hydroxy acids) connected in a ring. The residues are commonly but not necessarily regularly alternating.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estrutura 3D

Alvos associados (humanos)

PIN1 Tchem Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (36611 Activities)

Discover Target: PIN1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

A498 (42825 Activities)

Lot Number	Certificate Type	Data	Item
H2315400	Certificate of Analysis	Feb 07, 2025	E275307
H2315399	Certificate of Analysis	Feb 07, 2025	E275307
H2315297	Certificate of Analysis	Jul 28, 2023	E275307

Solubilidade	Soluble in DMSO to 5 mM
Sensibilidade	Moisture and light sensitive
Peso molecular	1101.300 g/mol
XLogP3	2.700
Hydrogen Bond Donor Count	4
Hydrogen Bond Acceptor Count	18
Rotatable Bond Count	7
Exact Mass	1100.42 Da
Monoisotopic Mass	1100.42 Da
Topological Polar Surface Area	352.000 Å²
Heavy Atom Count	77
Formal Charge	0
Complexity	2200.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	9
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1