Epertinib hydrochloride - ≥99% , CAS No.2071195-74-7

CAS: 2071195-74-7 Cat. No.: E413670 Fórmula: C30H28Cl2FN5O3 Peso molecular: 596.48 PubChem CID: 139290994
Disponível para encomenda
GRADE & PURITY ≥99%
Synonyms
Epertinib HCl | S-222611 hydrochloride | S-222611 HCl
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
Size
Alemanha (EU)
USA*
Price
Qty
1mg
E413670-1mg
Sob encomenda · 8–12 semanas
116,19€
5mg
E413670-5mg
Sob encomenda · 8–12 semanas
347,01€
10mg
E413670-10mg
Sob encomenda · 8–12 semanas
548,32€
25mg
E413670-25mg
Sob encomenda · 8–12 semanas
957,90€
50mg
E413670-50mg
Sob encomenda · 8–12 semanas
1339,70€
Enter a quantity for the sizes you want to add.
🧪

Why this grade

≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Information

Epertinib hydrochloride (S-222611 hydrochloride) is a potent, orally active, reversible, and selectivetyrosine kinaseinhibitor ofEGFR,HER2andHER4with IC50 of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib hydrochloride (S-222611 hydrochloride) exhibits antitumor activity.


Targets

EGFR (Cell-free assay); HER4 (Cell-free assay); HER2 (Cell-free assay) 1.48 nM; 2.49 nM; 7.15 nM

Specifications

Sinónimos
Epertinib HCl | S-222611 hydrochloride | S-222611 HCl
Especificações e pureza
≥99%
Mecanismos bioquímicos e fisiológicos
Epertinib hydrochloride (S-222611 hydrochloride) is a potent, orally active, reversible, and selective tyrosine kinase inhibitor of EGFR, HER2 and HER4 with IC50 of 1.48 nM, 7.15 nM and 2.49 nM, respectively. Epertinib hydrochloride (S-222611 hydrochlorid
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Pureza
≥99%
Nomes e identificadores
Sorrisos canónicosCC#CC(=NOCC1COCCN1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl.Cl
IUPAC NameN-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-[(Z)-N-[[(3R)-morpholin-3-yl]methoxy]-C-prop-1-ynylcarbonimidoyl]quinazolin-4-amine;hydrochloride
InChIKeyNVWJPQQXBPWOOA-PLXRJBJVSA-N
INCHI1S/C30H27ClFN5O3.ClH/c1-2-4-27(37-40-18-24-17-38-12-11-33-24)21-7-9-28-25(14-21)30(35-19-34-28)36-23-8-10-29(26(31)15-23)39-16-20-5-3-6-22(32)13-20;/h3,5-10,13-15,19,24,33H,11-12,16-18H2,1H3,(H,34,35,36);1H/b37-27+;/t24-;/m1./s1
PubChem CID 139290994
Peso molecular 596.48

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estrutura 3D
Modelo de Estrutura Química Interativa





Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriedades químicas e físicas
SolubilidadeSolubility (25°C) In vitro DMSO: 100 mg/mL (167.65 mM); Water: Insoluble; Ethanol: Insoluble;
SensibilidadeMoisture sensitive
Calculadoras de soluções
Revisões

Avaliações dos Clientes

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