Esomeprazole sodium - 10mM in DMSO , Potassium-transporting ATPase inhibitor, CAS No.161796-78-7, Potassium-transporting ATPase inhibitor

CAS: 161796-78-7 Cat. No.: E408295 Fórmula: C₁₇H₁₈N₃NaO₃S Peso molecular: 367.41 Número CE: 620-470-6

GRADE & PURITY 10mM in DMSO

Synonyms

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Information

Esomeprazole sodium Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

1H-Benzimidazole, 6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, sodium salt (1:1)

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Mecanismo de ação

Potassium-transporting ATPase inhibitor

Nomes e identificadores

• SMILES isoméricas: CC1=CN=C(C(=C1OC)C)C[S@](=O)C2=NC3=C([N-]2)C=C(C=C3)OC.[Na+]
• Peso molecular: 367.41
• Reaxy-Rn: 11512125
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=11512125&ln=

Propriedades químicas e físicas

• Ponto de ebulição (°C): 600°C
• Ponto de fusão (°C): 229 °C

Referências

1. Xiao-yu Xu, Zhe-yan Zhang, Xiao-dan Zhang, Jian-chao Luo, Yun-shan Zhong, Le-hao Jin, Da-peng Dai, Jian-chang Qian.  (2024)  Critical considerations for co-administering rivaroxaban and vonoprazan: Unveiling potential pharmacokinetic interactions.  CHEMICO-BIOLOGICAL INTERACTIONS,      [PMID:39643151] [10.1016/j.cbi.2024.111342]

Perguntas frequentes

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 161796-78-7, the molecular formula is C17H18N3NaO3S, and the molecular weight is 367.41 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.