Factor XIIIa

Cat. No.: np330963

GRADE & PURITY Bioactive, Native, EnzymoPure™, from Human plasma; Protein concentration: See COA

Accession #

P00488,P05160

Bioactivity

See COA

Visão geral

Human factor XIII is cleaved with human alpha thrombin that is immobilized to a resin. The thrombin is subsequently removed via chromatography. One plasma equivalent unit (PEU) is equal to ~108 Loewy units.

Buffer composition =  0.05mM EDTA/ 50% glycerol

Extinction Coefficient (1%)=13.8

Molecular Weight = 312,000 daltons

The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

If diluting, use physiologic buffer such as TBS containing 0.5mM EDTA.

Specifications

Product Name

Factor XIIIa

Sinónimos

Native Human Factor XIIIa protein | Human Factor XIIIa Native Protein | Coagulation Factor XIIIa, Human Plasma | Human Factor XIIIa | F13A1 | F13B | F13A | FXIIIB

Grau

Bioactive, Native, EnzymoPure™

Especificações e pureza

Bioactive, Native, EnzymoPure™, from Human plasma; Protein concentration: See COA

Mecanismos bioquímicos e fisiológicos

Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fib

Bioatividade

See COA

Número de acesso

P00488,P05160

Peso molecular previsto

312 kDa

Número da Comissão das Enzimas

EC 2.3.2.13

Tipo de molécula

Enzyme

Armazenamento e envio

Concentração

from Human plasma; Protein concentration: See COA

Condições de armazenamento de armazenamento

Store at -20°C,Avoid repeated freezing and thawing

Enviado em

Ice chest + Ice pads

Estabilidade e armazenamento

Store at -20℃ long term. Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Definição da unidade

One plasma equivalent unit (PEU) is equal to ~108 Loewy units.