γ-Fagarine - ≥98% , CAS No.524-15-2

CAS: 524-15-2 Cat. No.: F651688 Fórmula: C₁₃H₁₁NO₃ Peso molecular: 229.23 PubChem CID: 107936

GRAU & PUREZA ≥98%

Storage

Protected from light,Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

γ-Fagarine is a furoquinoline alkaloid naturally occurring in Rutae Herba . γ-Fagarine has strong anti- HCV activities with IC 50 of 20.4 μg/mL and is also a sister chromatid exchanges (SCEs) inducer

IC50& Target:IC50: 20.4 μg/mL (HCV)

Especificações

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

γ-Fagarine is a furoquinoline alkaloid naturally occurring in Rutae Herba . γ-Fagarine has strong anti- HCV activities with IC 50 of 20.4 μg/mL and is also a sister chromatid exchanges (SCEs) inducer.

Condições de armazenamento de armazenamento

Protected from light,Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Pureza

≥98%

Nomes e identificadores

Pubchem Sid

528768885

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528768885

SMILES isoméricas

COC1=CC=CC2=C1N=C3C(=C2OC)C=CO3

PubChem CID

107936

Peso molecular

229.23

Alvos associados (humanos)

ACHE Tclin Acetylcholinesterase (18204 Activities)

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ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)

Discover Target: ALDH1A1

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Raji (5516 Activities)

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HepG2 (196354 Activities)

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GNAS Tbio Guanine nucleotide-binding protein G(s), subunit alpha (103405 Activities)

Discover Target: GNAS

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BRCA1 Tchem Breast cancer type 1 susceptibility protein (15908 Activities)

Discover Target: BRCA1

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EHMT2 Tchem Histone-lysine N-methyltransferase, H3 lysine-9 specific 3 (93046 Activities)

Discover Target: EHMT2

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KDM4E Tchem Lysine-specific demethylase 4D-like (40243 Activities)

Discover Target: KDM4E

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HPGD Tchem 15-hydroxyprostaglandin dehydrogenase [NAD+] (24926 Activities)

Discover Target: HPGD

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MBNL1 Tbio Muscleblind-like protein 1 (34431 Activities)

Discover Target: MBNL1

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microRNA 21 (64692 Activities)

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ATAD5 Tbio ATPase family AAA domain-containing protein 5 (122566 Activities)

Discover Target: ATAD5

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Alvos associados (não humanos)

Trypsin (394 Activities)

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Mycobacterium tuberculosis (203094 Activities)

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Human immunodeficiency virus 1 (70413 Activities)

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Luciferin 4-monooxygenase (66902 Activities)

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Txnrd1 Thioredoxin reductase 1, cytoplasmic (45279 Activities)

Discover Target: Txnrd1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

NS1 Nonstructural protein 1 (33327 Activities)

Discover Target: NS1

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Mecanismos de ação

Propriedades químicas e físicas

• Sensibilidade: Light sensitive
• Peso molecular: 229.230 g/mol
• XLogP3: 2.900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 2
• Exact Mass: 229.074 Da
• Monoisotopic Mass: 229.074 Da
• Topological Polar Surface Area: 44.500 Ų
• Heavy Atom Count: 17
• Formal Charge: 0
• Complexity: 273.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1