1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
Sodium cholateis the sodium salt of cholic acid, a primary bile acid biosynthesized from cholesterol in the liver. In water at neutral pH it exists as a negatively charged (anionic) surfactant via its deprotonated carboxylate.
Sodium lauroyl sarcosinate is an amino-acid–based anionic surfactant used across personal and oral care—and in labs as “Sarkosyl”—valued as a milder, readily biodegradable alternative to harsher sulfates. Chemically, it couples a C12 lauroyl tail to N-methylglycine (sarcosine) through ...
Sodium deoxycholate (Na-DOC, CAS 302-95-4) is the sodium salt of deoxycholic acid, a naturally occurring secondary bile acid in mammals. It is produced in the intestine through bacterial 7α-dehydroxylation of cholic acid, one of the major primary bile acids synthesized in the liver from ...
Ionic surfactants are amphiphilic molecules whose headgroup is charged in water, so they bind to and disrupt lipid/protein surfaces while carrying either a negative (anionic), positive (cationic), or pH-dependent (amphoteric/zwitterionic) charge.
Cationic surfactants hold a unique place because of their positively charged headgroups, which interact strongly with negatively charged surfaces, from cell membranes and DNA molecules to clay minerals and silica particles.
Brij™ 35 (also sold as Brij™ L23); Laureth-23; polyoxyethylene (23) lauryl ether; tricosaethylene glycol monododecyl ether. CAS: 9002-92-0. It’s a nonionic ethoxylated fatty-alcohol surfactant derived from lauryl alcohol with an average of ~23 ethylene-oxide (EO) units (often abbreviated ...
Digitonin is a steroidal saponin (glycoside) classed and used as a mild, non-ionic detergent in biochemistry. It’s renowned for specific binding to membrane cholesterol, which underpins its selective permeabilization of the plasma membrane and its classic use in precipitating cholesterol ...
Poloxamers are amphiphilic triblock copolymers with the general formula HO–(EO)_a–(PO)_b–(EO)_a–H (EO = ethylene oxide, PO = propylene oxide). In water they self-assemble into micelles and, for some grades at sufficient concentration, form thermoreversible gels. Commercial families ...
Non-ionic surfactants are indispensable tools in modern science, pharmaceuticals, food technology, and cosmetics, where they function as emulsifiers, stabilizers, and solubilizers. Among them, Tween 20 (Polysorbate 20, CAS 9005-64-5) and Tween 80 (Polysorbate 80, CAS 9005-65-6) are two of the ...
