1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.
Antibodies are valuable tools in both basic research and therapeutic applications. Protein A, Protein G, and Protein L affinity agarose beads are classical laboratory tools for antibody purification. They achieve efficient purification by specifically binding antibodies and separating them from ...
Enzymes are highly efficient and specific biological catalysts, most of which are proteins. They can significantly accelerate the rate of biochemical reactions without altering the reaction equilibrium.
Protein precipitation is a classical technique in the early stages of protein purification. Its advantages include simple equipment, convenient operation, and the ability to concentrate samples while retaining yield. However, purity improvement is limited, so it is mainly used for preliminary ...
Immunoprecipitation (IP) utilizes the specific binding of antibodies to capture target proteins from complex samples. Protein A, G, and L agarose beads serve as solid-phase supports to efficiently bind antibodies, enabling precise separation.
Fluorescent-labeled peptides are a class of bioactive peptides covalently conjugated with fluorescent moieties, enabling molecular-level visualization with high sensitivity, safety, and cost-effectiveness.
Peptides are the fundamental structural units of proteins, consisting of specific sequences of amino acids linked by peptide bonds. Peptides composed of two amino acids are called dipeptides, those of three amino acids are called tripeptides, and so on. In cosmetics, commonly used peptides are ...
The UPS is the primary pathway for protein degradation within cells. It tags specific substrate proteins with ubiquitin (Ub), which are then recognized by the 26S proteasome and degraded into small peptides. This system maintains protein homeostasis and regulates processes such as the cell ...
Disulfide-containing peptides and diselenide-containing peptides are important molecules in peptide research and drug development. They stabilize the spatial conformation of peptide chains through covalent bridging, thereby maintaining or enhancing biological activity. Diselenide-containing ...
Proteases are widely present in cells and play a critical role in protein degradation and homeostasis regulation. However, during biochemical and molecular biology experiments, samples are susceptible to degradation by endogenous proteases during lysis or purification, which can lead to loss or ...
