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Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.

5929 articles
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Fluorescent probes – brightening the horizon of biomedical research

In 1998, the field of medical science marked a major milestone when Robert F. Furchgott, Louis J. Ignarro, and Ferid Murad were awarded the Nobel Prize in Physiology or Medicine for uncovering the role of nitric oxide (NO) as a key signaling molecule in the cardiovascular system. This ...

2025-06-10 03:33:53 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Burgess reagent

The Burgess reagent, (Methoxycarbonylsulfamoyl)triethylammonium hydroxide is a commercially available compound that has historically found utility as a dehydrating agent. The reagent may also be used to oxidize primary and secondary alcohols to their corresponding aldehydes and ketones in ...

2025-06-10 03:33:53 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

N-Bromosuccinimide (NBS)

N-Bromosuccinimide (NBS) is a brominating and oxidizing agent that is used as source for bromine in radical reactions (for example: allylic brominations) and various electrophilic additions. The NBS bromination of substrates such as alcohols and amines, followed by elimination of HBr in the ...

2025-06-10 03:33:53 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Trimethylamine borane / Borane trimethylamine complex

Trimethylamine borane, also known as trimethylamine complex with borane or trimethylamine borane adduct, is a chemical compound with the formula (CH3)3N·BH3. It is a coordination complex formed by the reaction between trimethylamine (N(CH3)3) and borane (BH3).

2025-06-10 03:33:53 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Method and Precautions of SDS-PAGE Gel Preparation

SDS-PAGE (sodium dodecyl sulfate-polyacrylamide gel electrophoresis) is a commonly used technique to separate proteins based on size. By denaturating the protein and giving it a uniform negative charge, the protein migrates to the positive pole under the application of an electric field and is ...

2025-06-10 03:33:53 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Boranes (Dimethylsulfide Borane, Borane-Tetrahydrofuran Complex)

Diborane (B2H6), the simplest borane, is a useful reagent with many applications, but it is pyrophoric, gaseous and not convenient to handle. There is a wide range of boranes: Decaborane for example is not as reactive as diborane and is used as reducing agent too.

2025-06-10 03:33:53 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Guidelines For Common Cell Culture Media

Cell culture medium is an indispensable part of cell biology research, which provides essential nutrients and a suitable develope environment for cells. The following is a comprehensive introduction to the detailed components and characteristics of several commonly used cell culture media:

2025-06-10 03:33:53 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Bis(pinacolato)diboron, B2pin2

Bis(pinacolato)diboron is a covalent compound containing two boron atoms and two pinacolato ligands. It has the formula [(CH3)4C2O2B]2; the pinacol groups are sometimes abbreviated as "pin", so the structure is sometimes represented as B2pin2. It is a colourless solid that is soluble in organic ...

2025-06-10 03:33:53 Updated
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