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Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

1,700+ technical articles by Aladdin Scientific's scientists on reagent selection, reaction mechanisms, assay design and formulation. New every week.

5935 articles
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Nucleic acid electrophoresis applications - preparative and analytical electrophoresis

Nucleic acid electrophoresis is used in many molecular biology research applications to test experimental results, and sometimes to isolate and purify samples for subsequent applications. Therefore, the application of conventional nucleic acid electrophoresis can generally be divided into ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Preparation and functionalized design of novel graphene-based nanostructures

At its inception, graphene was essentially a game for physicists. It was difficult to synthesize sufficient quantities of high-quality graphene, and it was not until researchers prepared monolayer graphene by simple mechanical peeling of graphite using tape that this new material with excellent ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Functional group protection and deprotection in oligonucleotide synthesis

Artificial synthesis of nucleic acids has now become an important technique in biochemistry and a great deal of technical experience has been accumulated today. The key to the efficient synthesis of nucleic acids lies in the proper protection and deprotection of functional groups during the ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Nucleic Acid Electrophoresis Additional Considerations–7 Aspects

The nucleic acid electrophoresis workflow requires the execution of several steps, each of which may affect the result of nucleic acid separation. This page discusses 7 additional considerations related to samples, reagents, and operating parameters, including: Nucleic acid sequence and ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

EGF Signaling: Tracking the path of Cancer

The epidermal growth factor (EGF) family is a group of structurally related proteins that regulate cell proliferation, migration and differentiation through tyrosine kinase receptors on target cells. EGF receptors have a cytoplasmic tyrosine kinase domain, a transmembrane domain, and an ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

PEG-Azide-Alkyne—Bioorthogonal and Click Chemistry

Bioorthogonal chemistry refers to a series of reactions that occur in a biological environment without affecting biomolecules or interfering with biochemical processes. For this purpose, the reaction must meet the following requirements: fast, efficient, and specific. • pH: The reaction must ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Nucleotide Synthesis in Cancer Cells

In neoplastic cells, the de novo synthesis of nucleotides is responsible for maintaining sufficient nucleotide libraries to support DNA replication and RNA production. The metabolic pathways that support nucleotide production are dependent on metabolic intermediates provided by glycolysis and ...

2025-06-10 03:33:47 Updated
Technical Articles: Reagent Chemistry, Synthesis & Bioscience Guides

Use process of combined carbonization dialysis bag

Dialysis is the process of selective diffusion of substances through membranes. It can be used to separate solutes with different molecular weights. Substances with molecular weights lower than the membrane interception threshold can diffuse through the membrane, while substances with molecular ...

2025-06-10 03:33:46 Updated
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