≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels , with IC 50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls.
In Vitro
Fluxametamide is an antagonist of GABA- and glutamate-gated chloride channels, dose-dependently inhibits currents induced by GABA and glutamate in M. domestica GABACls and GluCls, with IC 50 values of 1.95 (1.18-3.21) nM and 225 (137-372) nM, respectively, and displays potent antagonistic activity against T. urticae GABACls with an IC 50 of 0.219 (0.127-0.381) nM. Fluxametamide inhibits GABA responses in the wild-type L. striatellus GABACls with IC 50 values of 1.40 (0.57-3.29) nM; in the A2′N mutant GABACls, the IC 50 value is 3.51 (2.17-5.69) nM. Moreover, Fluxametamide scarcely inhibits GABA (EC 50 )-induced currents in rat GABACls at 10 μM and with no inhibition on glycine (EC 50 )-induced current in human α1 GlyCls at tested concentrations. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
Fluxametamide shows significant insecticidal activity with an LD 50 (LD 95 ) value of 12.9 ± 4.9 ng/fly (38.7 ± 6.3 ng/fly) . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:IC50: 1.95 nM ( M. domestica GABACls), 225 nM ( M. domestica GluCls)
Specifications
Especificações e pureza
≥98%
Mecanismos bioquímicos e fisiológicos
Fluxametamide is an insecticide with wide spectrum, acts as an antagonist of GABA- and glutamate-gated chloride channels , with IC 50 of 1.95 nM and 225 nM for M. domestica GABACls and GluCls.
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
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Revisões
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Perguntas frequentes
What is the purity of this product?
This product is supplied at ≥98% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 928783-29-3, the molecular formula is C20H16Cl2F3N3O3, and the molecular weight is 474.26 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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