Furosemide sodium - 10mM in DMSO , CAS No.41733-55-5

CAS: 41733-55-5 Cat. No.: F423888 Fórmula: C₁₂H₁₀ClN₂NaO₅S Peso molecular: 352.73 Número CE: 255-526-5 PubChem CID: 23673593

GRAU & PUREZA 10mM in DMSO

Synonyms

D07999 | Sodium furosemide | sodium;4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoate | Frosemide sodium | Q27251094 | HY-B0135A | FUROSEMIDE SODIUM [WHO-DD] | SODIUM 4-CHLORO-2-(2-FURYLMETHYLAMINO)-5-SULFAMOYL-BENZOATE | Benzoic acid, 5-(aminosulfon

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Information

Furosemide (Frusemide) sodium is a potent and orally active inhibitor ofNa-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist ofgamma-aminobutyric acid type A (GABAA) receptor.

Targets

NKCC ; GABAA receptor

Especificações

Sinónimos

D07999 | Sodium furosemide | sodium;4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoate | Frosemide sodium | Q27251094 | HY-B0135A | FUROSEMIDE SODIUM [WHO-DD] | SODIUM 4-CHLORO-2-(2-FURYLMETHYLAMINO)-5-SULFAMOYL-BENZOATE | Benzoic acid, 5-(aminosulfon

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Furosemide (Frusemide) sodium is a potent and orally active inhibitor of Na-K-Cl cotransporter (NKCC). Furosemide sodium is a subtype-selective antagonist of gamma-aminobutyric acid type A (GABAA) receptor.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Propriedades do produto

ALogP

-0.071

Contagem HBD

2

Ligação rotativa

5

Nomes e identificadores

Pubchem Sid

528775829

Sorrisos canónicos

C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)[O-])S(=O)(=O)N)Cl.[Na+]

IUPAC Name

sodium;4-chloro-2-(furan-2-ylmethylamino)-5-sulfamoylbenzoate

InChIKey

DLFCAVBMDSKMEY-UHFFFAOYSA-M

INCHI

1S/C12H11ClN2O5S.Na/c13-9-5-10(15-6-7-2-1-3-20-7)8(12(16)17)4-11(9)21(14,18)19;/h1-5,15H,6H2,(H,16,17)(H2,14,18,19);/q;+1/p-1

SMILES isoméricas

C1=COC(=C1)CNC2=CC(=C(C=C2C(=O)[O-])S(=O)(=O)N)Cl.[Na+]

PubChem CID

23673593

Peso molecular

352.73

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Benzenesulfonamides

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Benzenesulfonamides
• Intermediate Tree Nodes: Not available
• Direct Parent: Aminobenzenesulfonamides
• Alternative Parents: 4-halobenzoic acids Aminobenzoic acids Halobenzoic acids Benzenesulfonyl compounds Benzoic acids Aniline and substituted anilines Benzoyl derivatives Phenylalkylamines Secondary alkylarylamines Chlorobenzenes Organosulfonamides Aryl chlorides Heteroaromatic compounds Furans Vinylogous amides Aminosulfonyl compounds Carboxylic acid salts Amino acids Carboxylic acids Oxacyclic compounds Organic metal halides Organic oxides Organic sodium salts Organic zwitterions Organochlorides Organooxygen compounds Hydrocarbon derivatives
• Molecular Framework: Aromatic heteromonocyclic compounds
• Substituents: Aminobenzenesulfonamide - Aminobenzoic acid - Aminobenzoic acid or derivatives - Halobenzoic acid - 4-halobenzoic acid - Halobenzoic acid or derivatives - 4-halobenzoic acid or derivatives - Benzenesulfonyl group - Benzoic acid or derivatives - Benzoic acid - Benzoyl - Phenylalkylamine - Aniline or substituted anilines - Chlorobenzene - Halobenzene - Secondary aliphatic/aromatic amine - Aralkylamine - Organosulfonic acid amide - Aryl chloride - Aryl halide - Heteroaromatic compound - Furan - Organic sulfonic acid or derivatives - Organosulfonic acid or derivatives - Vinylogous amide - Sulfonyl - Aminosulfonyl compound - Amino acid - Carboxylic acid salt - Amino acid or derivatives - Secondary amine - Organoheterocyclic compound - Organic metal halide - Oxacycle - Carboxylic acid derivative - Carboxylic acid - Organic alkali metal salt - Organic oxide - Organic sodium salt - Organohalogen compound - Organochloride - Organonitrogen compound - Amine - Hydrocarbon derivative - Organooxygen compound - Organic nitrogen compound - Organic oxygen compound - Organosulfur compound - Organic salt - Organic zwitterion - Aromatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as aminobenzenesulfonamides. These are organic compounds containing a benzenesulfonamide moiety with an amine group attached to the benzene ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• DMSO (mg/mL) Solubilidade máxima: 71
• DMSO (mM) Solubilidade máxima: 201.287103450231
• Água (mg/mL) Solubilidade máxima: 71
• Água (mM) Solubilidade máxima: 201.287103450231
• Peso molecular: 352.730 g/mol
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 5
• Exact Mass: 351.99 Da
• Monoisotopic Mass: 351.99 Da
• Topological Polar Surface Area: 134.000 Ų
• Heavy Atom Count: 22
• Formal Charge: 0
• Complexity: 486.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 2

XLogP3