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GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist
In Vivo
GDC-0927 is a novel, potent, non-steroidal, orally bioavailable, selective ER antagonist/ER degrader (SERD) that induces tumor regression in estrogen receptor (ER)+breast cancer (BC) patient-derived xenograft models . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
IC50& Target:Estrogen receptor
| CAS | 1642297-01-5 |
|---|---|
| Sinónimos | GDC-0927 free base | HY-111484 | BG166429 | BS-16112 | SCHEMBL16325181 | US10227334, Example 3 | BCP29507 | Q50825069 | GDC 0927 | NSC-812902 | GDC0927 | GDC-0927 | 1642297-01-5 (free base) | 1-PIPERIDINEETHANOL, 4-HYDROXY-.ALPHA.-(4-HYDROXYPHENYL)-.BETA. |
| Especificações e pureza | ≥99% |
| Condições de armazenamento de armazenamento | Store at -20°C |
| Enviado em | Ice chest + Ice pads |
| Product Description | GDC-0927 (SRN-927) is a potent, non-steroidal, orally bioavailable, selective estrogen receptor antagonist In Vivo GDC-0927 is a novel, potent, non-steroidal, orally bioavailable, selective ER antagonist/ER degrader (SERD) that induces tumor regression in estrogen receptor (ER)+breast cancer (BC) patient-derived xenograft models . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Estrogen receptor |
| Solubilidade | DMSO : 83.33 mg/mL (180.56 mM; Need ultrasonic) |
| PubChem CID | 87055263 |