Glipizide - Moligand™, 10mM in DMSO , Sulfonylurea receptor 1, Kir6.2 blocker, CAS No.29094-61-9, Sulfonylurea receptor 1, Kir6.2 blocker

CAS: 29094-61-9 Cat. No.: G408514 Fórmula: C₂₁H₂₇N₅O₄S Peso molecular: 445.54 Número CE: 249-427-6

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

CP-28720 | N-​[2-​[4-​[[[(cyclohexylamino)​carbonyl]​amino]​sulfonyl]​phenyl]​ethyl]​-​5-​methyl-2-​pyrazinecarboxamide

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Information

Glipizide Glipizide (CP-28720) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.
In vitro

In vivo

Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

CP-28720 | N-​[2-​[4-​[[[(cyclohexylamino)​carbonyl]​amino]​sulfonyl]​phenyl]​ethyl]​-​5-​methyl-2-​pyrazinecarboxamide

Especificações e pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Glipizide (CP-28720) is used to treat high blood sugar levels caused by a type of diabetes mellitus called type 2 diabetes.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Tipo de ação

BLOCKER

Mecanismo de ação

Sulfonylurea receptor 1, Kir6.2 blocker

Propriedades do produto

• ALogP: 1.9

Nomes e identificadores

• SMILES isoméricas: CC1=CN=C(C=N1)C(=O)NCCC2=CC=C(C=C2)S(=O)(=O)NC(=O)NC3CCCCC3
• WGK Alemanha: 3
• RTECS: YS7640000
• Peso molecular: 445.54
• Reaxy-Rn: 903495
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=903495&ln=

Propriedades químicas e físicas

• Ponto de fusão (°C): 206 °C

Referências

1. Zixian He, Zhiwei Liu, Haihuan Xie, Pengjie Luo, Xiangmei Li.  (2023)  An Ultrasensitive Lateral Flow Immunoassay Based on Metal-Organic Framework-Decorated Polydopamine for Multiple Sulfonylureas Adulteration in Functional Foods.  Foods,  12  (3): (539).  [PMID:36766067] [10.3390/foods12030539]

2. Sun Zhiping, He Lingli, Yang Qingqing, Zhang Haizhi, Xu Weiren, Qin Xinguang, Liu Gang, Hu Zhongze, Zhang Luyong, Liu Changxiao.  (2022)  Study on the Effect of Three CYP2C9 Variants on Drug–Drug Interaction Related to Six Drugs In Vitro by LC–MS/MS Method.  CHROMATOGRAPHIA,  85  (3): (221-231).  [PMID:] [10.1007/s10337-021-04126-8]

3. Haihuan Xie, Yingying Li, Jin Wang, Yi Lei, Anastasios Koidis, Xiangmei Li, Xing Shen, Zhenlin Xu, Hongtao Lei.  (2021)  Broad-specific immunochromatography for simultaneous detection of various sulfonylureas in adulterated multi-herbal tea.  FOOD CHEMISTRY,      [PMID:34536782] [10.1016/j.foodchem.2021.131055]

4. Zhengyong Wang, Yuqi Cao, Yingjie Lu, Fang Zhang, Yue Su, Yinlong Guo.  (2020)  Ultrasonic extraction and nebulization in real-time coupled with carbon fiber ionization mass spectrometry for rapid screening of the synthetic drugs adulterated into herbal products.  ANALYTICA CHIMICA ACTA,      [PMID:33081950] [10.1016/j.aca.2020.08.045]

5. Yuanzhe Li, Mengying Yan, Xie He, Cunman Liang, Heng Liu, Qian Zhu, Mingqiang Wang, Xinhui Lu, Yi Lu, Ni Zhao.  (2025)  Organic electrochemical transceiver: An all-in-one sense-and-release device architecture for physiological modulation.  Science Advances,  11  (37):   [PMID:40939000] [10.1126/sciadv.adu9516]