Gold nanoparticles - 15nm diameter, amine functionalized, PEG 5000 coated, OD 50, dispersion in H₂O

Cat. No.: G486029

GRADE & PURITY 15nm diameter, amine functionalized, PEG 5000 coated, OD 50, dispersion in H₂O

Synonyms

Gold nanoparticles NH₂ functionalized, Gold Colloid, Au NP NH₂

Storage

Store at 2-8°C

Shipped In

Wet ice

Visão geral

Description

Gold nanoparticles (AuNPs) ranging from 2-200nm in diameter find applications in diverse fields. They show excellent biocompatibility and attractive physicochemical properties. Poly (ethylene) glycol (PEG) surface coatings on gold nanoparticles help in the reduction of protein adsorption, reduce nonspecific interactions with cells and greatly improve the pharmokinetics of these nanoparticles and reduce aggregation of the nanoparticles. PEG layer density depends inversely on the AuNP curvature. Denser coating was possible on smaller AuNPs. AuNPs coated with PEG 5000 exhibited highest colloidal stability. Amine functionalized GNPs which have Poly Ethylene Glycol (PEG) as the ligand or carrier molecule forms a conjugate with siRNA and is extremely useful in RNAi technology. Since it adheres to cell membranes, it may find use in cellular and intracellular targeting in targeted drug delivery applications and also used in biodistribution studies.††††Functionalized particles have been extensively used to study cellular uptake of nanoparticles and targeted drug delivery.Used in carrying siRNA which acts against human prostate carcinoma cells by inhibiting a specific cancer gene.

Specifications

Sinónimos

Gold nanoparticles NH₂ functionalized, Gold Colloid, Au NP NH₂

Especificações e pureza

15nm diameter, amine functionalized, PEG 5000 coated, OD 50, dispersion in H₂O

Condições de armazenamento de armazenamento

Store at 2-8°C

Enviado em

Wet ice

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Propriedades químicas e físicas

• Solubilidade: water: miscible