Gramine - 10mM in DMSO , CAS No.87-52-5

CAS: 87-52-5 Cat. No.: G408192 Fórmula: C11H14N2 Peso molecular: 174.24 Beilstein Registry Number: 140521 Número CE: 201-749-8
Disponível para encomenda
GRADE & PURITY 10mM in DMSO
Synonyms
(1H-indol-3-yl)-N,N-dimethylmethanamine
Storage
Store at -80°C
Shipped In
Dry ice packs + Cold packs
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Size
Alemanha (EU)
USA*
Price
Qty
1ml
G408192-1ml
—
2 Em stock

48,51€

71,07€
Gravar 22,56 € (31.75%)
Enter a quantity for the sizes you want to add.
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Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 4 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Information

Gramine (Donaxine) is a natural indole alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50 of 3.2 µM and 4.2 µM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic recept
In vitro


In vivo


Cell Data

cell lines:

Concentrations:

Incubation Time:

Powder Purity:≥97%

Specifications

Sinónimos
(1H-indol-3-yl)-N,N-dimethylmethanamine
Especificações e pureza
10mM in DMSO
Mecanismos bioquímicos e fisiológicos
Gramine (Donaxine) is a natural indole alkaloid isolated from giant reed, acts as an active adiponectin receptor (AdipoR) agonist, with IC50 of 3.2 µM and 4.2 µM for AdipoR2 and AdipoR1, respectively. Gramine is also a human and mouse β2-Adrenergic recept
Condições de armazenamento de armazenamento
Store at -80°C
Enviado em
Dry ice packs + Cold packs
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Nomes e identificadores
SMILES isoméricas CN(C)CC1=CNC2=CC=CC=C21
WGK Alemanha 3
RTECS NL7525000
Peso molecular 174.24
Beilstein 140521
Reaxy-Rn 140521
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=140521&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Alvos associados (humanos)
CYP2D6 Tclin Cytochrome P450 2D6 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriedades químicas e físicas
SolubilidadeSolubility (25°C) In vitro Ethanol: mg/mL    
Ponto de inflamação (°F)167℃
Ponto de inflamação (°C)167℃
Ponto de fusão (°C)132-134°C
FAQs e artigos
Citations of This Product
Referências
1. Gen-Qiang Chen, Yan-Fei Xia, Jin-Ming Yang, Zhi-Ping Che, Di Sun, Shen Li, Yue-E Tian, Sheng-Ming Liu, Jia Jiang, Xiao-Min Lin.  (2020)  Controlled synthesis of N, N-dimethylarylsulfonamide derivatives as nematicidal agents.  JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH,      [PMID:31773971] [10.1080/10286020.2019.1694513]
2. Zhang Chunhua, Wu Huiqin, Huang Xiaolan, Zhu Zhixin, Luo Huitai, Huang Fang, Lin Xiaoshan.  (2012)  Simultaneous Determination of Toxic Alkaloids in Blood and Urine by HPLC–ESI–MS/MS.  CHROMATOGRAPHIA,  75  (9): (499-511).  [PMID:] [10.1007/s10337-012-2216-6]
3. Lin-Song Teng, Zhen-Dong Ying, Xiao-Han Sun, Hao-Cheng Hou, Shi-Dong Qiu, Peng Liu, Ke-Jing Li, Lei Zhang, Xie-Huang Sheng.  (2025)  Formoterol, a clinically approved drug, inhibits ferroptosis by suppressing lipid peroxidation and attenuates APAP-induced acute liver injury.  CHEMICO-BIOLOGICAL INTERACTIONS,      [PMID:40914538] [10.1016/j.cbi.2025.111724]
4. Huiyu He, Rui Wang, Rongbin Nie, Nan Dong.  (2025)  An environmentally friendly cucurbit[7]uril-mediated magnetic-assisted matrix solid-phase dispersion extraction combined with HPLC-MS/MS for multiple analysis of pharmaceuticals and personal care products in aquatic organisms.  MICROCHEMICAL JOURNAL,      [PMID:] [10.1016/j.microc.2025.115146]
Calculadoras de soluções
Revisões

Avaliações dos Clientes

Perguntas frequentes

How should this product be stored?
Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 87-52-5, the molecular formula is C11H14N2, and the molecular weight is 174.24 g/mol.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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