GRF2 Mouse mAb - Primary antibody

Cat. No.: Ab106407

GRADE & PURITY See COA

Application

IF/ICC, IHC, WB

Host species

Mouse

Reactive species

Dog, Human, Monkey, Mouse, Rat

Isotype

Mouse IgG1

Clone Number

OTI2F5

Conjugation

Unconjugated

Visão geral

Mouse anti Human GRF2 Antibody, Monoclonal (OTI2F5), could be used for WB, IHC, IF/ICC and so on.

Specifications

Product Name

GRF2 Mouse mAb - Primary antibody

Sinónimos

C3G antibody | C3G protein antibody | CRK SH3 binding GNRP antibody | CRK SH3-binding GNRP antibody | DKFZp781P1719 antibody | GRF 2 antibody | GRF2 antibody | Guanine nucleotide releasing factor 2 (specific for crk proto oncogene) antibody | Guanine nucl

Especificações e pureza

See COA

Mecanismos bioquímicos e fisiológicos

Guanine nucleotide-releasing protein that binds to SH3 domain of CRK and GRB2/ASH. Transduces signals from CRK to activate RAS.

Espécie hospedeira

Mouse

Imunogénio

Recombinant full length protein of human RAPGEF1 produced in HKE293T cell.

Controlo positivo

WB: HepG2, HeLa, SVT2, A549, COS7, Jurkat, MDCK, PC12 and MCF7 lysates. IHC: Human breast, colon adenocarcinoma, ovary adenocarcinama, pancreas, thyroid, thyroid carcinoma, prostate carcinoma tissues. ICC/IF: COS7 cells.

Conjugação

Unconjugated

SDS-PAGE

150 kDa

Método de purificação

Protein A/G purified

Concentração

See COA

Armazenamento e envio

Forma

Liquid

Condições de armazenamento de armazenamento

Store at -20°C,Avoid repeated freezing and thawing

Enviado em

Ice chest + Ice pads

Estabilidade e armazenamento

Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon receipt, it is recommended to aliquot. Avoid freeze/thaw cycle.

Aplicação

• Aplicação: Dilution info
• IHC:

  1/150

• WB:

  1/400-1/4000

• IF/ICC:

  1:100 ;

Alvos associados (humanos)

RAPGEF1 Tbio Rap guanine nucleotide exchange factor 1 (0 Activities)

Discover Target: RAPGEF1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Perguntas frequentes

How should this product be stored?

Store at ?20 °C. Avoid repeated freeze–thaw cycles. Aliquot into single-use volumes before freezing.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

Which species reactivity has this antibody been validated against?

Validated reactivity is listed on the PDP and on each lot's datasheet. We validate against the most commonly tested species for the target (GRF2 Mouse mAb); cross-reactivity in untested species may exist but is not guaranteed. Contact technical support for specific species inquiries.