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· · COA & SDS Disponível para todos os produtos · Envio no mesmo dia em itens em estoque GSK 4112 - Moligand™, 10mM in DMSO , Agonist of Rev-Erb-α, CAS No.1216744-19-2, Agonist of Rev-Erb-α
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO Synonyms
tert-butyl 2-[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]acetate | tert-butyl 2-[(4-chlorophenyl)methyl-[(5-nitro-2-thienyl)methyl]amino]acetate | HY-14414 | GSK4112 | GSK-4112 | DTXSID701336675 | Rev-erbalpha agonist GS4112 | GTPL2903 | S
Shipped In
Dry ice packs + Cold packs
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Why this grade Moligand™, 10mM in DMSO Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.
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Quality documents SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Specifications Sinónimos
tert-butyl 2-[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]acetate | tert-butyl 2-[(4-chlorophenyl)methyl-[(5-nitro-2-thienyl)methyl]amino]acetate | HY-14414 | GSK4112 | GSK-4112 | DTXSID701336675 | Rev-erbalpha agonist GS4112 | GTPL2903 | S
Especificações e pureza
Moligand™, 10mM in DMSO
Mecanismos bioquímicos e fisiológicos
GSK4112 is a Rev-erbα agonist with EC50 of 0.4 μM, GSK4112 is a small-molecule chemical probe for the cellular biological study of the nuclear heme receptor REV-erbα.
Condições de armazenamento de armazenamento
Store at -80°C
Enviado em
Dry ice packs + Cold packs
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Mecanismo de ação
Agonist of Rev-Erb-α
Nomes e identificadores Sorrisos canónicos
CC(C)(C)OC(=O)CN(CC1=CC=C(C=C1)Cl)CC2=CC=C(S2)[N+](=O)[O-]
IUPAC Name
tert-butyl 2-[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]acetate
InChIKey
WYSLOKHVFKLWOU-UHFFFAOYSA-N
INCHI
1S/C18H21ClN2O4S/c1-18(2,3)25-17(22)12-20(10-13-4-6-14(19)7-5-13)11-15-8-9-16(26-15)21(23)24/h4-9H,10-12H2,1-3H3
SMILES isoméricas
CC(C)(C)OC(=O)CN(CC1=CC=C(C=C1)Cl)CC2=CC=C(S2)[N+](=O)[O-]
Reaxys-RN_link_address
https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=22650686&ln=
Documentation 📋 Safety Data Sheet (SDS) Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS → ✅ Certificate of Analysis (COA) Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA → 📊 Datasheet Quick-reference summary of product specifications and applications.
View datasheet → 🔬 Specification Sheet Full quality attributes and acceptance criteria for this grade.
View spec sheet →
Advanced Data Taxonomic Classification Kingdom Organic compounds Superclass Organic acids and derivatives Classe Carboxylic acids and derivatives Subclass Amino acids, peptides, and analogues Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives Direct Parent Alpha amino acid esters Alternative Parents 2-nitrothiophenes Phenylmethylamines Nitroaromatic compounds Benzylamines 2,5-disubstituted thiophenes Aralkylamines Chlorobenzenes Aryl chlorides Heteroaromatic compounds Trialkylamines Carboxylic acid esters Propargyl-type 1,3-dipolar organic compounds Organic oxoazanium compounds Monocarboxylic acids and derivatives Organochlorides Carbonyl compounds Hydrocarbon derivatives Organic oxides Organic salts Organic cations Molecular Framework Aromatic heteromonocyclic compounds Substituents Alpha-amino acid ester - 2-nitrothiophene - Nitrothiophene - Nitroaromatic compound - Benzylamine - Phenylmethylamine - Chlorobenzene - Halobenzene - 2,5-disubstituted thiophene - Aralkylamine - Monocyclic benzene moiety - Aryl halide - Aryl chloride - Benzenoid - Heteroaromatic compound - Thiophene - C-nitro compound - Carboxylic acid ester - Tertiary amine - Tertiary aliphatic amine - Organic nitro compound - Organic 1,3-dipolar compound - Monocarboxylic acid or derivatives - Propargyl-type 1,3-dipolar organic compound - Organic oxoazanium - Allyl-type 1,3-dipolar organic compound - Organoheterocyclic compound - Hydrocarbon derivative - Organic salt - Organohalogen compound - Organochloride - Amine - Organic nitrogen compound - Organonitrogen compound - Carbonyl group - Organic oxygen compound - Organooxygen compound - Organic oxide - Organic cation - Aromatic heteromonocyclic compound Descrição This compound belongs to the class of organic compounds known as alpha amino acid esters. These are ester derivatives of alpha amino acids. External Descriptors Not available Data sources 1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.
Estrutura 3D Alvos associados (humanos) Alvos associados (não humanos) Mecanismos de ação Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Peso molecular 396.900 g/mol XLogP3 4.700 Hydrogen Bond Donor Count 0 Hydrogen Bond Acceptor Count 6 Rotatable Bond Count 8 Exact Mass 396.091 Da Monoisotopic Mass 396.091 Da Topological Polar Surface Area 104.000 Ų Heavy Atom Count 26 Formal Charge 0 Complexity 487.000 Isotope Atom Count 0 Defined Atom Stereocenter Count 0 Undefined Atom Stereocenter Count 0 Defined Bond Stereocenter Count 0 Undefined Bond Stereocenter Count 0 The total count of all stereochemical bonds 0 Covalently-Bonded Unit Count 1
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View Moligand™ grade guide →
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