Guaifenesin - Moligand™, 10mM in DMSO , CAS No.93-14-1

CAS: 93-14-1 Cat. No.: G407746 Fórmula: C₁₀H₁₄O₄ Peso molecular: 198.22 Número CE: 202-222-5

GRADE & PURITY Moligand™, 10mM in DMSO

Synonyms

3-​(2-​methoxyphenoxy)​-1,​2-​propanediol

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

Information

Guaifenesin is an expectorant used to relieve chest congestion.
In vitro

In vivo

Guaifenesin (200 mg/kg, intravenously) combined with ketamine (50 mg/kg, intramuscularly) produces effective and safe surgical anesthesia for over 30 minutes in New Zealand white rabbits. Guaifenesin (200 mg/kg, intravenously) combined with ketamine (50 mg/kg, intramuscularly) mildly depresses respiratory rate but heart rate and arterial blood pressure are not significantly affected. Guaifenesin (200 mg/kg, intravenously) is combined with sodium pentobarbital (20 mg/kg, intravenously) to produce surgical anesthesia for a period of more than 30 minutes. Guaifenesin (50 mg/mL) combined Xylazine (0.1 mg/mL) and Ketamine (1.0 mg/mL) results in excellent anesthetic induction and maintenance with cardiopulmonary alterations similar to those associated with isoflurane in mechanically ventilated calves. Guaifenesin (150 mg/kg) decreases spectral edge frequency (SEF) and total power in pigs. Guaifenesin prevents adverse anesthetic induction events caused by Propofol in horse. Guaifenesin (90 mg/kg) followed by Propofol (3 mg/kg) should be sufficient to immobilize > 99% of calm healthy adult horses. Guaifenesin (100 mg/kg) produces moderate behavioral changes in the social conflict test in mice. Guaifenesin (200 mg/kg) combined with Paracetamol (200 mg/kg) causes significantly more pronounced analgesic effects that the corresponding doses of paracetamol alone in mice.
Cell Data

cell lines：

Concentrations：

Incubation Time：

Powder Purity:≥99%

Specifications

Sinónimos

3-​(2-​methoxyphenoxy)​-1,​2-​propanediol

Especificações e pureza

Moligand™, 10mM in DMSO

Mecanismos bioquímicos e fisiológicos

Guaifenesin is an expectorant used to relieve chest congestion.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Propriedades do produto

• ALogP: 1.4

Nomes e identificadores

• SMILES isoméricas: COC1=CC=CC=C1OCC(CO)O
• WGK Alemanha: 1
• RTECS: TY8400000
• Peso molecular: 198.22
• Reaxy-Rn: 3200276
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=3200276&ln=

Propriedades químicas e físicas

• Ponto de ebulição (°C): 215°C/19mm
• Ponto de fusão (°C): 83°C

Referências

1. Shuqi Guo, Falin He, Shaoyang Hu, Wansong Zong, Rutao Liu.  (2023)  Novel evidence on iodoacetic acid-induced immune protein functional and conformational changes: Focusing on cellular and molecular aspects.  SCIENCE OF THE TOTAL ENVIRONMENT,      [PMID:38103599] [10.1016/j.scitotenv.2023.169359]

2. Yuanjiao Liu, Yi Wang, Songyao Zhang, Hengqi Zou, Xinrui Miao, Wenli Deng.  (2023)  Fabricating 2D Host −Guest Kagomé Packing for C2-Symmetric Aromatic Carboxylic Acids with Different Spatial Configuration: Different Ways, Same Destination.  Journal of Physical Chemistry C,      [PMID:] [10.1021/acs.jpcc.2c08436]

3. Yongzhi San, Minghua Wang.  (2025)  Cordycepin Ameliorates Kainic Acid-Induced HT22 Cell Neurotoxicity by Activating GPR120-Mediated Mitophagy.  Developmental Neurobiology,  85  (2): (e22961).  [PMID:40007070] [10.1002/dneu.22961]

Perguntas frequentes

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?80 °C. Ultra-low temperature storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships frozen with dry ice and cold packs. Unpack on arrival and transfer it to the storage condition stated above; handle dry ice with insulated gloves in a ventilated area.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 93-14-1, the molecular formula is C10H14O4, and the molecular weight is 198.22 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.