H10 - ≥98%(HPLC) , CAS No.2084811-68-5

CAS: 2084811-68-5 Cat. No.: H288586 Fórmula: C₂₄H₂₇N₇O₇S Peso molecular: 557.58

GRADE & PURITY ≥98%(HPLC)

Synonyms

3-(N-(2-(4-(2-(4-((3-Carbamoylphenyl)amino)-4-oxobutanamido)ethyl)-1H-1,2,3-triazol-1-yl)ethyl)sulfamoyl)benzoic acid

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Specifications

Sinónimos

3-(N-(2-(4-(2-(4-((3-Carbamoylphenyl)amino)-4-oxobutanamido)ethyl)-1H-1,2,3-triazol-1-yl)ethyl)sulfamoyl)benzoic acid

Especificações e pureza

≥98%(HPLC)

Mecanismos bioquímicos e fisiológicos

PARP14 inhibitor (IC50= 490 nM). Exhibits ~ 24- and 18-fold selectivity for PARP14 over PARP1 and TNKS1, respectively. Binds both the nicotinamide and adenine sites on PARP14. Inhibits PARP14 and induces apoptosis in HepG2 and RPMI-8226 in cancer cellsin

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

ACTIVATOR

Pureza

≥98%(HPLC)

Nomes e identificadores

• Sorrisos canónicos: C1=CC(=CC(=C1)NC(=O)CCC(=O)NCCC2=CN(N=N2)CCNS(=O)(=O)C3=CC=CC(=C3)C(=O)O)C(=O)N
• IUPAC Name: 3-[2-[4-[2-[[4-(3-carbamoylanilino)-4-oxobutanoyl]amino]ethyl]triazol-1-yl]ethylsulfamoyl]benzoic acid
• InChIKey: MUOMSHSMJCWQFH-UHFFFAOYSA-N
• INCHI: 1S/C24H27N7O7S/c25-23(34)16-3-1-5-18(13-16)28-22(33)8-7-21(32)26-10-9-19-15-31(30-29-19)12-11-27-39(37,38)20-6-2-4-17(14-20)24(35)36/h1-6,13-15,27H,7-12H2,(H2,25,34)(H,26,32)(H,28,33)(H,35,36)
• SMILES isoméricas: C1=CC(=CC(=C1)NC(=O)CCC(=O)NCCC2=CN(N=N2)CCNS(=O)(=O)C3=CC=CC(=C3)C(=O)O)C(=O)N
• Peso molecular: 557.58
• Reaxy-Rn: 30590087
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=30590087&ln=

Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: Solvent:DMSO, Max Conc. mg/mL: 27.88, Max Conc. mM: 50

Perguntas frequentes

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2084811-68-5, the molecular formula is C??H??N?O?S, and the molecular weight is 557.58 g/mol. InChIKey MUOMSHSMJCWQFH-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.