Harman-d , CAS No.1216708-84-7

CAS: 1216708-84-7 Cat. No.: H1443675 Fórmula: C12H7D3N2 Peso molecular: 185.24 PubChem CID: 46781679
Disponível para encomenda
Storage
Store at -20°C
Shipped In
Ice chest + Ice pads
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Size
Alemanha (EU)
USA*
Price
Qty
1mg
H1443675-1mg
Sob encomenda · 8–12 semanas
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Why this grade

for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Harman-d 3 is deuterium labeled Harmane. Harmane is a benzodiazepine receptor inhibitor ( IC 50 =7 μM), with IC 50 values for mACh , Opioid Receptor , MAO-A/B , and α2-adrenergic receptor of 24 μM, 2.8 μM, 0.5 μM, 5 μM, and 18 μM, respectively. Harmane also inhibits haloperidol and serotonin , with IC 50 values of 163 μM and 101 μM, respectively. Harmane inhibits the I1 imidazoline receptor ( IC 50 =30 nM) to reduce blood pressure and has antidepressant, anti-anxiety, anticonvulsant, and analgesic effects. Harmane inhibits dopamine biosynthesis by decreasing tyrosine hydroxylase (TH) activity and enhancing L-DOPA-induced cytotoxicity in PC12 cells. Additionally, Harmane can increase the mutagenic effect induced by 2-acetylaminofluorene (AAF).

Specifications

Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Nomes e identificadores
Sorrisos canónicosCC1=NC=CC2=C1NC3=CC=CC=C23
IUPAC Name1-(trideuteriomethyl)-9H-pyrido[3,4-b]indole
InChIKeyPSFDQSOCUJVVGF-FIBGUPNXSA-N
INCHI1S/C12H10N2/c1-8-12-10(6-7-13-8)9-4-2-3-5-11(9)14-12/h2-7,14H,1H3/i1D3
SMILES isoméricas [2H]C([2H])([2H])C1=NC=CC2=C1NC3=CC=CC=C23
PubChem CID 46781679
Peso molecular 185.24

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Estrutura 3D
Modelo de Estrutura Química Interativa





Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Calculadoras de soluções
Revisões

Avaliações dos Clientes

Perguntas frequentes

How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 1216708-84-7, the molecular formula is C12H7D3N2, and the molecular weight is 185.24 g/mol. InChIKey PSFDQSOCUJVVGF-FIBGUPNXSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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