Factor VIIa, CAS No.65312-43-8

CAS: 65312-43-8 Cat. No.: H1442061 Número CE: 633-213-8

GRADE & PURITY Bioactive, ActiBioPure™, Native, High Performance, EnzymoPure™, ≥95%(SDS-PAGE), from Human plasma; Pre-lyophilization Protein Concentration: See COA

Accession #

P08709

Bioactivity

See COA

Visão geral

  Prepared from purified Human Factor VII using Human Factor XIIa. The Factor Xlla is removed using affinity chromatography. Purity is determined by SDS-PAGE. Human Factor VIIa reduces to 29,500 and 23,500 with the addition of 2-mercaptoethanol. Activity is determined via clotting assay. Factor Vlla, in the presence of calcium ions and Tissue factor, activates Factors IX and X to their enzymatically active forms, Factor IXa and Xa.

  Extinction Coefficient (1%) = 13.9

  The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.

Specifications

Product Name

Factor VIIa, CAS No.65312-43-8

Sinónimos

Human Factor VIIa Native Protein | Coagulation Factor VIIa, Human Plasma | coagulation factor VIIa | Coagulation factor VII | F7 | SPCA

Grau

ActiBioPure™, Bioactive, High Performance, Native, EnzymoPure™

Especificações e pureza

Bioactive,ActiBioPure™,Native,High Performance,EnzymoPure™,≥95%(SDS-PAGE),from Human plasma; Pre-lyophilization Protein Concentration: See COA

Mecanismos bioquímicos e fisiológicos

Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue

Bioatividade

See COA

Número de acesso

P08709

Peso molecular previsto

50 kDa

CAS

65312-43-8

Número da Comissão das Enzimas

EC 3.4.21.21

Tipo de molécula

Enzyme

Product Line

Produtos biológicos

Armazenamento e envio

Concentração

from Human plasma; Pre-lyophilization Protein Concentration: See COA

Reconstituição

We suggest hydrating the protein with a good quality water to the original volume (See COA). After hydration aliquot into a useful (one time use) size and freeze at -80℃.

Condições de armazenamento de armazenamento

Store at 2-8°C

Enviado em

Wet ice

Estabilidade e armazenamento

Store at 2-8℃ long term. Upon reconstitution, it is recommended to aliquot and freeze at -80℃.

Perguntas frequentes

What is the purity of this product, and how is it determined?

This product is supplied at ≥95% purity, determined by SDS-PAGE. Lot-specific values are stated on the Certificate of Analysis.

What is ActiBioPure??

ActiBioPure? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, ActiBioPure? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

What does Bioactive mean?

Bioactive indicates that the product has been processed and tested for biological and biochemical applications. Specifications may include endotoxin limits, microbial controls, sterility, low DNase/RNase/protease activity, and verified biological activity where relevant.

How should this product be stored?

Store at 2–8 °C. Refrigerated storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 65312-43-8.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.