ILK-IN-3 - 10mM in DMSO , CAS No.6975-75-3

CAS: 6975-75-3 Cat. No.: I655677 Fórmula: C₁₀H₁₂N₆O Peso molecular: 232.24 PubChem CID: 228619

GRADE & PURITY 10mM in DMSO

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Visão geral

ILK-IN-3 is an orally active integrin linked kinase (ILK) inhibitor. ILK-IN-3 improves the anticancer efficacy of Docetaxel in orthotopic LCC6 model.

In Vitro

ILK-IN-3 (compound 4, 10 μM) inhibits DYRK1, GSK3α/β, CDK5/p25 kinase activity to 17%, 51%, 47%, 95%, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

ILK-IN-3 (QLT0267) (200 mg/kg，口服，28 天) 抑制原位 LCC6 模型中的肿瘤生长 。 MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Specifications

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

ILK-IN-3 is an orally active integrin linked kinase (ILK) inhibitor. ILK-IN-3 improves the anticancer efficacy of Docetaxel ( HY-B0011 ) in orthotopic LCC6 model.

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Nomes e identificadores

SMILES isoméricas

COC1=CC=C(C=C1)N=NC2=C(NN=C2N)N

PubChem CID

228619

Peso molecular

232.24