IMR-1A - ≥97% , CAS No.331862-41-0

CAS: 331862-41-0 Cat. No.: I412257 Fórmula: C₁₃H₁₁NO₅S₂ Peso molecular: 325.36

GRADE & PURITY ≥97%

Synonyms

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Information

IMR-1A IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

Targets

Notch (Cell-free assay); Notch (Cell-free assay) 0.5 μM; 2.9 μM(Kd)

Specifications

Sinónimos

Acetic acid,2-​[2-​methoxy-​4-​[(4-​oxo-​2-​thioxo-​5-​thiazolidinylidene)​methyl]​phenoxy]​-

Especificações e pureza

≥97%

Mecanismos bioquímicos e fisiológicos

IMR-1A, an acid metabolite of IMR-1, is a potent inhibitor of Notch with IC50 of 0.5 μM and Kd of 2.9 μM. IMR-1A exhibits anti-tumor activity.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Pureza

≥97%

Propriedades do produto

• ALogP: 2.29
• hba_count: 4
• Contagem HBD: 1
• Ligação rotativa: 5

Nomes e identificadores

• Pubchem Sid: 488191798
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488191798
• Sorrisos canónicos: COC1=C(C=CC(=C1)C=C2C(=O)NC(=S)S2)OCC(=O)O
• IUPAC Name: 2-[2-methoxy-4-[(E)-(4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]phenoxy]acetic acid
• InChIKey: DVBJNSKWHSGTDK-BJMVGYQFSA-N
• INCHI: 1S/C13H11NO5S2/c1-18-9-4-7(2-3-8(9)19-6-11(15)16)5-10-12(17)14-13(20)21-10/h2-5H,6H2,1H3,(H,15,16)(H,14,17,20)/b10-5+
• Peso molecular: 325.36
• Reaxy-Rn: 29764446
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=29764446&ln=

Propriedades químicas e físicas

• Solubilidade: Solubility (25°C) In vitro DMSO: 6 mg/mL (18.44 mM); Water: Insoluble; Ethanol: Insoluble
• DMSO (mg/mL) Solubilidade máxima: 6
• DMSO (mM) Solubilidade máxima: 18.4411113843128
• Água (mg/mL) Solubilidade máxima: ＜1

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥97% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 331862-41-0, the molecular formula is C13H11NO5S2, and the molecular weight is 325.36 g/mol. InChIKey DVBJNSKWHSGTDK-BJMVGYQFSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.