INDY - ≥98% , CAS No.1169755-45-6

CAS: 1169755-45-6 Cat. No.: I275280 Fórmula: C₁₂H₁₃NO₂S Peso molecular: 235.3

GRADE & PURITY ≥98%

Synonyms

(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone | (Z)-1-(3-ethyl-5-hydroxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Visão geral

Shipped at Room Temperature. Store at +4°C short term (1-2 weeks). Store at -20°C.

Specifications

Sinónimos

(1Z)-1-(3-Ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone | (Z)-1-(3-ethyl-5-hydroxybenzo[d]thiazol-2(3H)-ylidene)propan-2-one

Especificações e pureza

≥98%

Mecanismos bioquímicos e fisiológicos

Potent DYRK1A/B inhibitor (IC 50 values are 0.23 and 0.24\xa0µM for DYRK1B and DYRK1A respectively). Also inhibits DYRK2, DTRK4, CLK1, CLK4, casein kinase 1 and PIM1 (> 90% inhibition at 10 μM).

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Nota

Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Pureza

≥98%

Nomes e identificadores

• Pubchem Sid: 488202143
• Pubchem Sid Url: https://pubchem.ncbi.nlm.nih.gov/substance/488202143
• Sorrisos canónicos: CCN1C2=C(C=CC(=C2)O)SC1=CC(=O)C
• IUPAC Name: 1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one
• InChIKey: GCSZJMUFYOAHFY-UHFFFAOYSA-N
• INCHI: 1S/C12H13NO2S/c1-3-13-10-7-9(15)4-5-11(10)16-12(13)6-8(2)14/h4-7,15H,3H2,1-2H3
• SMILES isoméricas: CCN1C2=C(C=CC(=C2)O)SC1=CC(=O)C
• Peso molecular: 235.3
• Reaxy-Rn: 28418243
• Reaxys-RN_link_address: https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=28418243&ln=

Propriedades químicas e físicas

• Solubilidade: Soluble in DMSO to 100 mM