IONIS-MAPTRx - ≥94% , CAS No.2857842-32-9

CAS: 2857842-32-9 Cat. No.: I651209 Peso molecular: 7182.00

GRAU & PUREZA ≥94%

Storage

Store at 2-8°C,Desiccated

Shipped In

Wet ice

Visão geral

IONIS-MAPTRx (BIIB080) is the first Tau-lowering antisense oligonucleotide (ASO). IONIS-MAPTRx has the potential for the research of Alzheimer Disease.

In Vivo

Intrathecal administrations of IONIS-MAPTRx in nonhuman primates showed a mean MAPT mRNA reduction of 77% in frontal cortex and 74% in hippocampus without dose-limiting side effects . MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Form:Solid

Especificações

Especificações e pureza

≥94%

Mecanismos bioquímicos e fisiológicos

IONIS-MAPTRx (BIIB080) is the first Tau-lowering antisense oligonucleotide (ASO). IONIS-MAPTRx has the potential for the research of Alzheimer Disease.

Condições de armazenamento de armazenamento

Store at 2-8°C,Desiccated

Enviado em

Wet ice

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

INHIBITOR

Pureza

≥94%

Nomes e identificadores

Peso molecular

7182.00

Propriedades químicas e físicas

• Solubilidade: H2O : 50 mg/mL (6.96 mM; Need ultrasonic)

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥94% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

How should this product be stored?

Store at 2–8 °C, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.

How is this product shipped?

This product ships chilled on wet ice. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 2857842-32-9, and the molecular weight is 7182.00 g/mol.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.