Irresistin-16 - Moligand™, ≥98% , CAS No.2624247-60-3

CAS: 2624247-60-3 Cat. No.: I611149 Fórmula: C₂₃H₁₉N₅ Peso molecular: 365.43

GRADE & PURITY Moligand™, ≥98%

Synonyms

IRS-16 | IRS16 | 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-([1,1'-biphenyl]-4-ylmethyl)- | IRS-16

Storage

Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Visão geral

Irresistin-16, an SCH 79797 derivative, is a broad spectrum bactericidal antibiotic that is effective in both gram-positive and gram-negative bacteria and exhibits low frequency of resistance. Irresistin-16 act through interruption of bacterial folate metabolism and bacterial membrane integrity. It inhibits E. coli dihydrofolate reductase FolA. Irresistin-16 is effective in mouse gonorrhea infection model.

Specifications

Sinónimos

IRS-16 | IRS16 | 7H-Pyrrolo[3,2-f]quinazoline-1,3-diamine, 7-([1,1'-biphenyl]-4-ylmethyl)- | IRS-16

Especificações e pureza

Moligand™, ≥98%

Condições de armazenamento de armazenamento

Store at -20°C,Argon charged

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Pureza

≥98%

Nomes e identificadores

• Sorrisos canónicos: Nc1nc(N)c2c(n1)ccc1c2ccn1Cc1ccc(cc1)c1ccccc1
• IUPAC Name: 7-[(4-phenylphenyl)methyl]pyrrolo[3,2-f]quinazoline-1,3-diamine
• InChIKey: CKQXMSDRDDHCOR-UHFFFAOYSA-N
• INCHI: 1S/C23H19N5/c24-22-21-18-12-13-28(20(18)11-10-19(21)26-23(25)27-22)14-15-6-8-17(9-7-15)16-4-2-1-3-5-16/h1-13H,14H2,(H4,24,25,26,27)
• Peso molecular: 365.43

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Benzenoids
    • Classe Benzene and substituted derivatives
      • Subclass Biphenyls and derivatives

• Kingdom: Organic compounds
• Superclass: Benzenoids
• Classe: Benzene and substituted derivatives
• Subclass: Biphenyls and derivatives
• Intermediate Tree Nodes: Not available
• Direct Parent: Biphenyls and derivatives
• Alternative Parents: Quinazolinamines N-alkylindoles Indoles Aminopyrimidines and derivatives Substituted pyrroles Imidolactams Heteroaromatic compounds Azacyclic compounds Primary amines Hydrocarbon derivatives
• Molecular Framework: Aromatic heteropolycyclic compounds
• Substituents: Biphenyl - Quinazolinamine - N-alkylindole - Quinazoline - Indole - Indole or derivatives - Aminopyrimidine - Imidolactam - Substituted pyrrole - Pyrimidine - Heteroaromatic compound - Pyrrole - Organoheterocyclic compound - Azacycle - Hydrocarbon derivative - Primary amine - Organonitrogen compound - Amine - Organic nitrogen compound - Aromatic heteropolycyclic compound
• Descrição: This compound belongs to the class of organic compounds known as biphenyls and derivatives. These are organic compounds containing to benzene rings linked together by a C-C bond.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

SLC2A1 Tchem Solute carrier family 2, facilitated glucose transporter member 1 (1 Activities)

Discover Target: SLC2A1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

SLC2A1 Tchem Glucose transporter (14755 Activities)

Discover Target: SLC2A1

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HepG2 (196354 Activities)

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Alvos associados (não humanos)

Pseudomonas aeruginosa (123386 Activities)

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Klebsiella pneumoniae (43867 Activities)

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Staphylococcus aureus (210822 Activities)

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Acinetobacter baumannii (41033 Activities)

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Enterococcus faecium (13803 Activities)

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Plasmodium falciparum (966862 Activities)

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Enterobacter sp. (336 Activities)

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Mecanismos de ação