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JHU 37152 - 10mM in DMSO , CAS No.2369979-67-7

JHU 37152 - 10mM in DMSO , CAS No.2369979-67-7

Name: JHU 37152 - 10mM in DMSO , CAS No.2369979-67-7
SKU: J422779
Availability: InStock

CAS: 2369979-67-7 Cat. No.: J422779 Fórmula: C₁₉H₂₀ClFN₄ Peso molecular: 358.85

COA

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JHU 37152 - 10mM in DMSO CAS No(2369979-67-7) by Aladdin Scientific

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Disponível para encomenda

GRADE & PURITY 10mM in DMSO

Synonyms

8-Chloro-11-(4-ethylpiperazin-1-yl)-1-fluoro-5H-dibenzo[b,e][1,4]diazepine

Storage

Store at -80°C

Shipped In

Dry ice packs + Cold packs

Specifications Nomes e identificadores Documentation Advanced Data Taxonomic Classification Estrutura 3D Certificados（CoA,COO,BSE/TSE e Mapa de Análise) Propriedades químicas e físicas Calculadoras de soluções Revisões

🧪

Why this grade

10mM in DMSO for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

🌡

Storage & shipping

Store at -80°C Ships Dry ice packs + Cold packs Check lot-specific COA for exact specifications.

📋

Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

📚

Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Specifications

Sinónimos

8-Chloro-11-(4-ethylpiperazin-1-yl)-1-fluoro-5H-dibenzo[b,e][1,4]diazepine

Especificações e pureza

10mM in DMSO

Mecanismos bioquímicos e fisiológicos

High affinity and highly potent activator of hM3Dqand hM4DiDREADDs (Kivalues are 1.8 nM and 8.7 nM for hM3Dqand hM4Diin vitro, respectively; EC50values are 5 nM and 0.5 nM for hM3Dqand hM4Diin vitro, respectively). Selectively displaces [3H]clozapine from

Condições de armazenamento de armazenamento

Store at -80°C

Enviado em

Dry ice packs + Cold packs

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Tipo de ação

AGONIST

Nomes e identificadores

Pubchem Sid

528764981

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/528764981

Sorrisos canónicos

CCN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=C2C(=CC=C4)F

IUPAC Name

3-chloro-6-(4-ethylpiperazin-1-yl)-7-fluoro-11H-benzo[b][1,4]benzodiazepine

InChIKey

NZMZJNNWMSYDNX-UHFFFAOYSA-N

INCHI

1S/C19H20ClFN4/c1-2-24-8-10-25(11-9-24)19-18-14(21)4-3-5-16(18)22-15-7-6-13(20)12-17(15)23-19/h3-7,12,22H,2,8-11H2,1H3

Peso molecular

358.85

Reaxy-Rn

34970282

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=34970282&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

Kingdom Organic compounds
- Superclass Organoheterocyclic compounds
  - Classe Benzodiazepines
    - Subclass Dibenzodiazepines

Kingdom	Organic compounds
Superclass	Organoheterocyclic compounds
Classe	Benzodiazepines
Subclass	Dibenzodiazepines
Intermediate Tree Nodes	Not available
Direct Parent	Dibenzodiazepines
Alternative Parents	1,4-benzodiazepines N-alkylpiperazines 1,4-diazepines Imidolactams Benzenoids Trialkylamines Vinyl fluorides Vinyl chlorides Propargyl-type 1,3-dipolar organic compounds Fluoroalkenes Dialkylamines Chloroalkenes Carboximidamides Azacyclic compounds Amidines Organopnictogen compounds Organofluorides Organochlorides Hydrocarbon derivatives
Molecular Framework	Aromatic heteropolycyclic compounds
Substituents	Dibenzodiazepine - 1,4-benzodiazepine - N-alkylpiperazine - Para-diazepine - Imidolactam - Benzenoid - Piperazine - 1,4-diazinane - Tertiary aliphatic amine - Tertiary amine - Azacycle - Fluoroalkene - Chloroalkene - Haloalkene - Organic 1,3-dipolar compound - Propargyl-type 1,3-dipolar organic compound - Carboximidamide - Vinyl halide - Vinyl fluoride - Vinyl chloride - Secondary amine - Secondary aliphatic amine - Amidine - Organic nitrogen compound - Organopnictogen compound - Hydrocarbon derivative - Organonitrogen compound - Organofluoride - Organochloride - Organohalogen compound - Amine - Aromatic heteropolycyclic compound
Descrição	This compound belongs to the class of organic compounds known as dibenzodiazepines. These are compounds containing a dibenzodiazepine moiety, which consists of two benzene connected by diazepine ring.
External Descriptors	Not available
1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61. DOI: 10.1186/s13321-016-0174-y

Estrutura 3D

Certificados（CoA,COO,BSE/TSE e Mapa de Análise)

C of A & Other Certificates(BSE/TSE, COO):

Analytical Chart:

Find and download the COA for your product by matching the lot number on the packaging.

1 results found

Lot Number	Certificate Type	Data	Item
G2409583	Certificate of Analysis	May 19, 2026	J422779

Propriedades químicas e físicas

Peso molecular	358.800 g/mol
XLogP3	3.500
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	4
Rotatable Bond Count	2
Exact Mass	358.136 Da
Monoisotopic Mass	358.136 Da
Topological Polar Surface Area	30.900 Å²
Heavy Atom Count	25
Formal Charge	0
Complexity	494.000
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
The total count of all stereochemical bonds	0
Covalently-Bonded Unit Count	1

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Revisões

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