≥99% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
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Storage & shipping
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
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Quality documents
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
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Literature proof
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
Visão geral
JNJ-9350 is an inhibitor of spermine oxidase ( SMOX ) with an IC 50 value of 0.01 μM. JNJ-9350 also inhibits polyamine oxidase ( PAO ) with an IC 50 value of 0.79 μM. JNJ-9350 can be used for the research of cancer
In Vitro
JNJ-9350 (0-100 μM) shows inhibitory effect to SMOX, PAO and LSD1 with IC 50 values of 10 nM, 790 nM and ＞60 μM, respectively. JNJ-9350 (1.1-70 µM) binds with SMOX with a K i value of 9.9 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
1.19 Pharmacokinetic Properties of JNJ-9350 in Mice . Mice PO 10 mg/kg Clearance (mL/min/kg) (Total/Unbound) 73/5217 Volume of distribution (L/kg) 1.7 Half-life (min) 16 PPB (Mouse) 98.6% Oral F% 34% MCE has not independently confirmed the accuracy of these methods. They are for reference only.
JNJ-9350 is an inhibitor of spermine oxidase ( SMOX ) with an IC 50 value of 0.01 μM. JNJ-9350 also inhibits polyamine oxidase ( PAO ) with an IC 50 value of 0.79 μM. JNJ-9350 can be used for the research of cancer.
Condições de armazenamento de armazenamento
Store at -20°C
Enviado em
Ice chest + Ice pads
Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.
Tipo de ação
INHIBITOR
Pureza
≥99%
Nomes e identificadores
Peso molecular
422.48
Documentation
📋 Safety Data Sheet (SDS)
Comprehensive hazard, handling, storage, and regulatory compliance document.
DMSO : 5 mg/mL (11.83 mM; ultrasonic and warming and heat to 60°C)
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Perguntas frequentes
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 326923-09-5, the molecular formula is C25H22N6O, and the molecular weight is 422.48 g/mol.
How is this product shipped?
This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.
What is the purity of this product?
This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
How should this product be stored?
Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.
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