≥98% for sensitive chromatographic and analytical workflows requiring minimal baseline interference.
Store at -20°C Ships Ice chest + Ice pads Check lot-specific COA for exact specifications.
SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.
Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.
JR14a is an effective thiophene antagonist of human complement C3a receptor. JR14a has higher selectivity for human C3a receptor than C5a receptor. JR14a can inhibit C3aR-mediated inflammation
| Pubchem Sid | 488203061 |
|---|---|
| Pubchem Sid Url | https://pubchem.ncbi.nlm.nih.gov/substance/488203061 |
| Canonical Smiles | CC1=C(SC(=C1)C(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)C(=O)NC(CCCN=C(N)N)C(=O)O |
| IUPAC Name | (2S)-2-[[5-[bis(4-chlorophenyl)methyl]-3-methylthiophene-2-carbonyl]amino]-5-(diaminomethylideneamino)pentanoic acid |
| InChIKey | OHRIKWUZKGNQKQ-IBGZPJMESA-N |
| INCHI | 1S/C25H26Cl2N4O3S/c1-14-13-20(21(15-4-8-17(26)9-5-15)16-6-10-18(27)11-7-16)35-22(14)23(32)31-19(24(33)34)3-2-12-30-25(28)29/h4-11,13,19,21H,2-3,12H2,1H3,(H,31,32)(H,33,34)(H4,28,29,30)/t19-/m0/s1 |
| Isomeric SMILES | CC1=C(SC(=C1)C(C2=CC=C(C=C2)Cl)C3=CC=C(C=C3)Cl)C(=O)N[C@@H](CCCN=C(N)N)C(=O)O |
| PubChem CID | 145996525 |
| Molecular Weight | 533.47 |
Comprehensive hazard, handling, storage, and regulatory compliance document.
Download SDS →Lot-specific quality data. Enter your lot number to retrieve the exact COA.
Look up COA →Full quality attributes and acceptance criteria for this grade.
View spec sheet →| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 D2306283 | Certificate of Analysis | Feb 07, 2023 | J573257 |
| D2306285 | Certificate of Analysis | Feb 07, 2023 | J573257 |
| D2306307 | Certificate of Analysis | Feb 07, 2023 | J573257 |
| D2306356 | Certificate of Analysis | Feb 07, 2023 | J573257 |
| D2306357 | Certificate of Analysis | Feb 07, 2023 | J573257 |
| D2306360 | Certificate of Analysis | Feb 07, 2023 | J573257 |
| D2306371 | Certificate of Analysis | Feb 07, 2023 | J573257 |
| D2306449 | Certificate of Analysis | Feb 07, 2023 | J573257 |
| Molecular Weight | 533.500 g/mol |
|---|---|
| XLogP3 | 5.000 |
| Hydrogen Bond Donor Count | 4 |
| Hydrogen Bond Acceptor Count | 5 |
| Rotatable Bond Count | 10 |
| Exact Mass | 532.11 Da |
| Monoisotopic Mass | 532.11 Da |
| Topological Polar Surface Area | 159.000 Ų |
| Heavy Atom Count | 35 |
| Formal Charge | 0 |
| Complexity | 716.000 |
| Isotope Atom Count | 0 |
| Defined Atom Stereocenter Count | 1 |
| Undefined Atom Stereocenter Count | 0 |
| Defined Bond Stereocenter Count | 0 |
| Undefined Bond Stereocenter Count | 0 |
| The total count of all stereochemical bonds | 0 |
| Covalently-Bonded Unit Count | 1 |
