L-Cystine - Moligand™, ≥98%(HPLC) , CAS No.56-89-3

CAS: 56-89-3 Cat. No.: L432952 Fórmula: C₆H₁₂N₂O₄S₂ Peso molecular: 240.3 Beilstein Registry Number: 1728094 Número CE: 200-296-3

GRADE & PURITY Moligand™, ≥98%(HPLC)

Synonyms

b,b'-Dithiodialanine | CYSTINE (EP MONOGRAPH) | (R,R)-3,3'-dithiobis(2-aminopropanoic acid) | CYSTINE [INN] | Cystine [USAN] | CYSTINE [WHO-DD] | L-alpha-Diamino-beta-dithiolactic acid | L-CYSTINE [JAN] | L-Cystine, non-animal source | S-CYSTEINYL CYSTEIN

Storage

Room temperature

Shipped In

Normal

Visão geral

Application

L-Cystine has been used in in vitro cystine solubility assay to identify potential drugs that influence cystine solubility. It is also used as a supplement of phosphate-buffered saline to slice and wash periprosthetic tissues.

Specifications

Sinónimos

b,b'-Dithiodialanine | CYSTINE (EP MONOGRAPH) | (R,R)-3,3'-dithiobis(2-aminopropanoic acid) | CYSTINE [INN] | Cystine [USAN] | CYSTINE [WHO-DD] | L-alpha-Diamino-beta-dithiolactic acid | L-CYSTINE [JAN] | L-Cystine, non-animal source | S-CYSTEINYL CYSTEIN

Especificações e pureza

Moligand™, ≥98%(HPLC)

Mecanismos bioquímicos e fisiológicos

Cysteine is the source of disulfide linkages in proteins and has a role in sulfur transport. It undergoes rapid oxidation to form cystine at physiological pH. L-cystine is crucial for oxygen production and low density lipoprotein modification by arterial

Condições de armazenamento de armazenamento

Room temperature

Enviado em

Normal

Grau

Moligand™

Tipo de ação

ACTIVATOR

Pureza

≥98%(HPLC)

Nomes e identificadores

Pubchem Sid

504754186

Pubchem Sid Url

https://pubchem.ncbi.nlm.nih.gov/substance/504754186

Sorrisos canónicos

C([C@@H](C(=O)O)N)SSC[C@@H](C(=O)O)N

IUPAC Name

(2R)-2-amino-3-[[(2R)-2-amino-2-carboxyethyl]disulfanyl]propanoic acid

InChIKey

LEVWYRKDKASIDU-IMJSIDKUSA-N

INCHI

1S/C6H12N2O4S2/c7-3(5(9)10)1-13-14-2-4(8)6(11)12/h3-4H,1-2,7-8H2,(H,9,10)(H,11,12)/t3-,4-/m0/s1

SMILES isoméricas

C([C@@H](C(=O)O)N)SSC[C@@H](C(=O)O)N

WGK Alemanha

3

Peso molecular

240.3

Beilstein

1728094

Reaxy-Rn

1728094

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=1728094&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organic acids and derivatives
    • Classe Carboxylic acids and derivatives
      • Subclass Amino acids, peptides, and analogues
        • Level5 Amino acids and derivatives
          • Level6 Alpha amino acids and derivatives
            • Level7 Cysteine and derivatives
              • Level8 L-cysteine-S-conjugates

• Kingdom: Organic compounds
• Superclass: Organic acids and derivatives
• Classe: Carboxylic acids and derivatives
• Subclass: Amino acids, peptides, and analogues
• Intermediate Tree Nodes: Amino acids and derivatives - Alpha amino acids and derivatives - Cysteine and derivatives
• Direct Parent: L-cysteine-S-conjugates
• Alternative Parents: L-alpha-amino acids Dicarboxylic acids and derivatives Dialkyldisulfides Amino acids Sulfenyl compounds Carboxylic acids Organopnictogen compounds Organic oxides Monoalkylamines Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic acyclic compounds
• Substituents: L-cysteine-s-conjugate - Alpha-amino acid - L-alpha-amino acid - Dicarboxylic acid or derivatives - Organic disulfide - Dialkyldisulfide - Amino acid - Sulfenyl compound - Carboxylic acid - Organopnictogen compound - Organic nitrogen compound - Primary amine - Organosulfur compound - Organooxygen compound - Organonitrogen compound - Primary aliphatic amine - Organic oxygen compound - Carbonyl group - Hydrocarbon derivative - Amine - Organic oxide - Aliphatic acyclic compound
• Descrição: This compound belongs to the class of organic compounds known as l-cysteine-s-conjugates. These are compounds containing L-cysteine where the thio-group is conjugated.
• External Descriptors: non-proteinogenic L-alpha-amino acid - L-cysteine derivative - cystine

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Alvos associados (humanos)

F2 Tclin Thrombin (11687 Activities)

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ESR1 Tclin Estrogen receptor alpha (17718 Activities)

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PGR Tclin Progesterone receptor (8562 Activities)

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CHRM2 Tclin Muscarinic acetylcholine receptor M2 (10671 Activities)

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HTR1A Tclin Serotonin 1a (5-HT1a) receptor (14969 Activities)

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ADRA2A Tclin Alpha-2a adrenergic receptor (9450 Activities)

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AR Tclin Androgen Receptor (11781 Activities)

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CHRM1 Tclin Muscarinic acetylcholine receptor M1 (12690 Activities)

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GABRA1 Tclin GABA receptor alpha-1 subunit (399 Activities)

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MAOA Tclin Monoamine oxidase A (11911 Activities)

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DRD1 Tclin Dopamine D1 receptor (9720 Activities)

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ACHE Tclin Acetylcholinesterase (18204 Activities)

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PTGS1 Tclin Cyclooxygenase-1 (9233 Activities)

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SLC6A2 Tclin Norepinephrine transporter (10102 Activities)

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SLC6A4 Tclin Serotonin transporter (12625 Activities)

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ADRA1A Tclin Alpha-1a adrenergic receptor (8359 Activities)

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OPRM1 Tclin Mu opioid receptor (19785 Activities)

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DRD3 Tclin Dopamine D3 receptor (14368 Activities)

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SLC6A3 Tclin Dopamine transporter (10535 Activities)

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PDE3A Tclin Phosphodiesterase 3A (3309 Activities)

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HTR2B Tclin Serotonin 2b (5-HT2b) receptor (10323 Activities)

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TBXA2R Tclin Thromboxane A2 receptor (5717 Activities)

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PDE4A Tclin Phosphodiesterase 4A (1943 Activities)

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ADORA3 Tchem Adenosine A3 receptor (15931 Activities)

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HRH3 Tclin Histamine H3 receptor (10389 Activities)

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POLK Tbio DNA polymerase kappa (8653 Activities)

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Alvos associados (não humanos)

Hdac6 Histone deacetylase 6 (222 Activities)

Discover Target: Hdac6

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Mecanismos de ação

Propriedades químicas e físicas

• Solubilidade: 1 M HCl: 50mg/mL, clear, colorless to faintly yellow
• Rotação específica [α]: -222.5 ° (C=1, 1mol/L HCl)
• Ponto de fusão (°C): 260-261°C
• Peso molecular: 240.300 g/mol
• XLogP3: -6.300
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 7
• Exact Mass: 240.024 Da
• Monoisotopic Mass: 240.024 Da
• Topological Polar Surface Area: 177.000 Ų
• Heavy Atom Count: 14
• Formal Charge: 0
• Complexity: 192.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 2
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

What is the purity of this product, and how is it determined?

This product is supplied at ≥98% purity, determined by HPLC. Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at room temperature.

How is this product shipped?

This product ships under standard ambient conditions. No temperature-controlled packaging is required.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 56-89-3, the molecular formula is C6H12N2O4S2, and the molecular weight is 240.3 g/mol. InChIKey LEVWYRKDKASIDU-IMJSIDKUSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.