proteína quinase 3 ativada por mitógeno
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47 produtos
Produtos populares
- Selonsertib (GS-4997), Mitogen-activated protein kinase kinase kinase 5 inhibitorCAS: 1448428-04-3 Número CE: 822-332-2 PubChem CID: 71245288 Fórmula: C24H24FN7O Peso molecular: 445.49Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%● Em estoque — Armazém nos EUA, envio para a EU* Item #: S413964Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 5-(4-cyclopropylimidazol-1-yl)-2-fluoro-4-methyl-N-[6-(4-propan-2-yl-1,2,4-triazol-3-yl)pyridin-2-yl]benzamide
- SMILES
- CC1=CC(=C(C=C1N2C=C(N=C2)C3CC3)C(=O)NC4=CC=CC(=N4)C5=NN=CN5C(C)C)F
- InChIKey
- YIDDLAAKOYYGJG-UHFFFAOYSA-N
- InChI
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- Sinónimos
- AMY27913 | HY-18938 | 1448428-04-3 | (2S,SR)-METHIONINE SULFOXIMINE | EX-A1618 | GS 4997 | Selonsertib (GS-4997) | UN...
- Takinib, Inhibitor of CDC like kinase 2;Inhibitor of interleukin 1 receptor associated kinase 1;Inhibitor of interleukin 1 receptor associated kinase 4;Inhibitor of mitogen-activated protein kinase kinase kinase 7CAS: 1111556-37-6 Número CE: 841-675-9 PubChem CID: 37750349 Fórmula: C18H18N4O2 Peso molecular: 322.37Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. 10mM in DMSO● Em estoque — Armazém nos EUA, envio para a EU* Item #: T420617Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 3-N-(1-propylbenzimidazol-2-yl)benzene-1,3-dicarboxamide
- SMILES
- CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N
- InChIKey
- UOZVVPXKJGOFIG-UHFFFAOYSA-N
- InChI
- 1S/C18H18N4O2/c1-2-10-22-15-9-4-3-8-14(15)20-18(22)21-17(24)13-7-5-6-12(11-13)16(19)23/h3-9,11H,2,10H2,1H3,(H2,19,23)(H,20,21,24)
- Sinónimos
- N17080 | SCHEMBL20063046 | F0918-1884 | A928060 | Tox21_300612 | Diethyl phthalate, 99% | NSC789624 | NSC-789624 | UN...
- pelubiprofenCAS: 69956-77-0 PubChem CID: 5282203Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools.◐ .Sob encomenda · 8–12 semanas Item #: P612684Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 2-[4-[(E)-(2-oxocyclohexylidene)methyl]phenyl]propanoic acid
- SMILES
- CC(C1=CC=C(C=C1)C=C2CCCCC2=O)C(=O)O
- InChIKey
- AUZUGWXLBGZUPP-GXDHUFHOSA-N
- InChI
- 1S/C16H18O3/c1-11(16(18)19)13-8-6-12(7-9-13)10-14-4-2-3-5-15(14)17/h6-11H,2-5H2,1H3,(H,18,19)/b14-10+
- Sinónimos
- (+-)-p-(((E)-2-Oxocyclohexylidene)methyl)hydratropic acid | CAS-69956-77-0 | DB12150 | Q27251763 | Benzeneacetic acid...
- Cot inhibitor-1◐ .Sob encomenda · 8–12 semanas Item #: C646885Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- PF-05381941CAS: 1474022-02-0 Fórmula: C27H26N6O2 Peso molecular: 466.53◐ .Sob encomenda · 8–12 semanas Item #: P647400Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- TAK1/MAP4K2 inhibitor 1◐ .Sob encomenda · 8–12 semanas Item #: T648184Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- N-[4-[(4-ethylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(6-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]benzamide
- SMILES
- CCN1CCN(CC1)CC2=C(C=C(C=C2)NC(=O)C3=CC(=C(C=C3)C)OC4=NC=NC5=C4C=C(N5)C)C(F)(F)F
- InChIKey
- RWNAOXLCVXJMGM-UHFFFAOYSA-N
- InChI
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- Sinónimos
- AKOS016012030 | n-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-4-methyl-3-((6-methyl-7h-pyrrolo[2,3-...
- DLK-IN-1Solid ≥98%◐ .Sob encomenda · 8–12 semanas Item #: D650308Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 5-[5-[(1R,5S)-3-(oxetan-3-yl)-3-azabicyclo[3.1.0]hexan-6-yl]-1-propan-2-ylpyrazol-3-yl]-3-(trifluoromethoxy)pyridin-2-amine
- SMILES
- CC(C)N1C(=CC(=N1)C2=CC(=C(N=C2)N)OC(F)(F)F)C3C4C3CN(C4)C5COC5
- InChIKey
- UHEFRVBGJORHNV-UUVAVEHKSA-N
- InChI
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- SM1-71◐ .Sob encomenda · 8–12 semanas Item #: S646519Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- N-[2-[[5-chloro-2-[4-(4-methylpiperazin-1-yl)anilino]pyrimidin-4-yl]amino]phenyl]prop-2-enamide
- SMILES
- CN1CCN(CC1)C2=CC=C(C=C2)NC3=NC=C(C(=N3)NC4=CC=CC=C4NC(=O)C=C)Cl
- InChIKey
- SCMLGVPMSXTUNC-UHFFFAOYSA-N
- InChI
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- GNE-3511Solid Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%◐ .Sob encomenda · 8–12 semanas Item #: G647232Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 2-[[6-(3,3-difluoropyrrolidin-1-yl)-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile
- SMILES
- C1CN(CCC1C2=CC(=NC(=C2)N3CCC(C3)(F)F)NC4=NC=CC(=C4)C#N)C5COC5
- InChIKey
- RHFIAUKMKYHHFA-UHFFFAOYSA-N
- InChI
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- Sinónimos
- 2-((6-(3,3-Difluoropyrrolidin-1-yl)-4-(1-(oxetan-3-yl)piperidin-4-yl)pyridin-2-yl)amino)isonicotinonitrile
- ASK1-IN-2◐ .Sob encomenda · 8–12 semanas Item #: A648376Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 6-fluoro-N-[6-(4-propan-2-yl-1,2,4-triazol-3-yl)pyridin-2-yl]-1H-indole-2-carboxamide
- SMILES
- CC(C)N1C=NN=C1C2=NC(=CC=C2)NC(=O)C3=CC4=C(N3)C=C(C=C4)F
- InChIKey
- LYUQNMNUBOUCBX-UHFFFAOYSA-N
- InChI
- 1S/C19H17FN6O/c1-11(2)26-10-21-25-18(26)14-4-3-5-17(23-14)24-19(27)16-8-12-6-7-13(20)9-15(12)22-16/h3-11,22H,1-2H3,(H,23,24,27)
- TAK1-IN-4CAS: 1570374-32-1 Fórmula: C18H17N3O3 Peso molecular: 323.35◐ .Sob encomenda · 8–12 semanas Item #: T649901Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- SMILES
- O=C(C1=CC=CC(C(NC2=NC3=C(N2CCC)C=CC=C3)=O)=C1)O
- Cot inhibitor-2◐ .Sob encomenda · 8–12 semanas Item #: C650545Ver ProdutoPreços e tamanhos do pacote
Identificadores técnicos
- Nome IUPAC
- 8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-carbonitrile
- SMILES
- CCN1CCC(CC1)N2C=C(N=N2)CNC3=CC4=C(C(=CN=C4C(=C3)Cl)C#N)NC5=CC(=C(C=C5)F)Cl
- InChIKey
- PHNZIIMWDVXPGG-UHFFFAOYSA-N
- InChI
- show more
- Sinónimos
- BDBM29923 | 8-chloro-4-(3-chloro-4-fluoroanilino)-6-[[1-(1-ethylpiperidin-4-yl)triazol-4-yl]methylamino]quinoline-3-c...
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Perguntas frequentes
How is the MAP3K listing put together?
It draws on reported MAP3K annotations within MAPK/ERK Pathway and lists each compound with its structure, identifiers, and the activity published for it. Always check the underlying assay before comparing potency values across entries.
How do I choose a MAP3K modulator for my assay?
Start from the assay format and readout — biochemical, cell-based, or in vivo — then compare the MAP3K entries on potency, selectivity over related family members, and solubility in your vehicle. Where several chemotypes are available, a reference compound plus a structurally unrelated backup is the usual way to control for off-target effects.
Which specifications matter most for MAP3K compounds?
Purity and identity confirmation come first, then solubility in DMSO or your chosen vehicle, recommended storage temperature, and stability in solution. For MAP3K work in particular, freshly prepared stocks avoid most of the reproducibility problems seen with stored plates. All products are supplied for professional research and development use only, and are not for use in humans, animals, diagnostics, or therapy.
What if the MAP3K compound I need is not listed?
Search by CAS number or SMILES first, since analogs of MAP3K compounds are often catalogued under a related target. Custom synthesis and bulk enquiries go to [email protected]. We supply verified businesses, research institutions, universities, and government agencies.