LY 367385 - Moligand™, ≥99% , Antagonist of mGlu 1 receptor, CAS No.198419-91-9, Antagonist of mGlu 1 receptor

CAS: 198419-91-9 Cat. No.: L274915 Fórmula: C10H11NO4 Peso molecular: 209.2
Disponível para encomenda
GRADE & PURITY Moligand™ ? Moligand™ — Aladdin's line of ligands and bioactive small molecules. Use for receptor, pathway, and binding studies needing defined small-molecule tools. ≥99%
Synonyms
HB0398 | HMS3372C21 | (S)-2-(4-Carboxy-2-methylphenyl)glycine | 2-Amino-4-oxo-6-methylpyrimidine | NCGC00025067-02 | Q27083034 | YHA41991 | (S)-(+)-alpha-Amino-4-carboxy-2-methylbenzeneaceticacid | (S)-4-(amino(carboxy)methyl)-3-methylbenzoic acid | BENZE
Storage
Room temperature,Desiccated
Shipped In
Normal
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Size
Alemanha (EU)
USA*
Price
Qty
10mg
L274915-10mg
Sob encomenda · 8–12 semanas
166,52€
50mg
L274915-50mg
Sob encomenda · 8–12 semanas
746,17€
Enter a quantity for the sizes you want to add.
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Why this grade

Moligand™, ≥99% Moligand™ for sensitive chromatographic and analytical workflows requiring minimal baseline interference.

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Storage & shipping

Room temperature,Desiccated Ships Normal Check lot-specific COA for exact specifications.

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Quality documents

SDS, COA, datasheet, and spec sheet available for download. Lot-specific COA accessible via lot number lookup.

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Literature proof

Cited in 0 peer-reviewed publications across chromatography, organic synthesis, and cross-coupling reactions.

Visão geral

Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.

Specifications

Sinónimos
HB0398 | HMS3372C21 | (S)-2-(4-Carboxy-2-methylphenyl)glycine | 2-Amino-4-oxo-6-methylpyrimidine | NCGC00025067-02 | Q27083034 | YHA41991 | (S)-(+)-alpha-Amino-4-carboxy-2-methylbenzeneaceticacid | (S)-4-(amino(carboxy)methyl)-3-methylbenzoic acid | BENZE
Especificações e pureza
Moligand™, ≥99%
Mecanismos bioquímicos e fisiológicos
Potent, selective mGlu 1a antagonist. Neuroprotective and anticonvulsant in vivo .
Condições de armazenamento de armazenamento
Room temperature,Desiccated
Enviado em
Normal
Grau
Moligand™
Tipo de ação
ANTAGONIST
Mecanismo de ação
Antagonist of mGlu 1 receptor
Nota
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Pureza
≥99%
Nomes e identificadores
Sorrisos canónicosCC1=C(C=CC(=C1)C(=O)O)C(C(=O)O)N
IUPAC Name4-[(S)-amino(carboxy)methyl]-3-methylbenzoic acid
InChIKeySGIKDIUCJAUSRD-QMMMGPOBSA-N
INCHI1S/C10H11NO4/c1-5-4-6(9(12)13)2-3-7(5)8(11)10(14)15/h2-4,8H,11H2,1H3,(H,12,13)(H,14,15)/t8-/m0/s1
SMILES isoméricas CC1=C(C=CC(=C1)C(=O)O)[C@@H](C(=O)O)N
Peso molecular 209.2
Reaxy-Rn 7974812
Reaxys-RN_link_address https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=7974812&ln=

Documentation

📋 Safety Data Sheet (SDS)

Comprehensive hazard, handling, storage, and regulatory compliance document.

Download SDS →

✅ Certificate of Analysis (COA)

Lot-specific quality data. Enter your lot number to retrieve the exact COA.

Look up COA →

📊 Datasheet

Quick-reference summary of product specifications and applications.

View datasheet →

🔬 Specification Sheet

Full quality attributes and acceptance criteria for this grade.

View spec sheet →

Advanced Data

Taxonomic Classification

Taxonomy Tree

KingdomOrganic compounds
SuperclassOrganic acids and derivatives
ClasseCarboxylic acids and derivatives
SubclassAmino acids, peptides, and analogues
Intermediate Tree Nodes Amino acids and derivatives - Alpha amino acids and derivatives - Alpha amino acids
Direct ParentL-alpha-amino acids
Alternative Parents Benzoic acids  Benzoyl derivatives  Toluenes  Aralkylamines  Amino acids  Monocarboxylic acids and derivatives  Carboxylic acids  Organic oxides  Monoalkylamines  Hydrocarbon derivatives  Carbonyl compounds  
Molecular FrameworkAromatic homomonocyclic compounds
Substituents L-alpha-amino acid - Benzoic acid or derivatives - Benzoic acid - Benzoyl - Aralkylamine - Toluene - Monocyclic benzene moiety - Benzenoid - Amino acid - Carboxylic acid - Monocarboxylic acid or derivatives - Organonitrogen compound - Primary aliphatic amine - Hydrocarbon derivative - Carbonyl group - Amine - Organic oxygen compound - Organic nitrogen compound - Organic oxide - Organooxygen compound - Primary amine - Aromatic homomonocyclic compound
DescriçãoThis compound belongs to the class of organic compounds known as l-alpha-amino acids. These are alpha amino acids which have the L-configuration of the alpha-carbon atom.
External Descriptors Not available
Estrutura 3D
Modelo de Estrutura Química Interativa





Alvos associados (humanos)
GRM1 Tchem Metabotropic glutamate receptor 1 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM1 Tchem Metabotropic glutamate receptor 1 (2309 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
GRM5 Tchem Metabotropic glutamate receptor 5 (5733 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
APEX1 Tchem DNA-(apurinic or apyrimidinic site) lyase (38016 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Alvos associados (não humanos)
ffp 4'-phosphopantetheinyl transferase ffp (24982 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mecanismos de ação
Certificados(CoA,COO,BSE/TSE e Mapa de Análise)
C of A & Other Certificates(BSE/TSE, COO):
Analytical Chart:
Propriedades químicas e físicas
SolubilidadeSoluble in 1.1 eq. NaOH to 100 mM
Peso molecular209.200 g/mol
XLogP3-1.800
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count3
Exact Mass209.069 Da
Monoisotopic Mass209.069 Da
Topological Polar Surface Area101.000 Ų
Heavy Atom Count15
Formal Charge0
Complexity266.000
Isotope Atom Count0
Defined Atom Stereocenter Count1
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
The total count of all stereochemical bonds0
Covalently-Bonded Unit Count1
Calculadoras de soluções
Revisões

Avaliações dos Clientes

Perguntas frequentes

What is the purity of this product?
This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.
What is Moligand??
Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.
How should this product be stored?
Store at room temperature, desiccated. Keep the container tightly closed with desiccant — the material is moisture-sensitive.
How is this product shipped?
This product ships under standard ambient conditions. No temperature-controlled packaging is required.
What are the CAS number, molecular formula and molecular weight?
The CAS Number is 198419-91-9, the molecular formula is C10H11NO4, and the molecular weight is 209.2 g/mol. InChIKey SGIKDIUCJAUSRD-QMMMGPOBSA-N.
What documentation is provided?
Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.

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