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LY2922470 is a potent, selective and orally available agonist of the G protein-coupled receptor 40 (GPR40) , with EC 50 s of 7 nM, 1 nM and 3 nM for human GPR40, mouse GPR40 and rat GPR40, respectively. LY2922470 reduces glucose levels along with significant increases in insulin and GLP-1 , is potential for the treatment of type 2 diabetes mellitus (T2DM)
IC50& Target:EC50:7 nM (human GPR40), 1 nM (mouse GPR40), 3 nM (rat GPR40)
| CAS | 1423018-12-5 |
|---|---|
| Concentração | 10mM in DMSO |
| Especificações e pureza | 10mM in DMSO |
| Condições de armazenamento de armazenamento | Protected from light,Store at -80°C |
| Enviado em | Dry ice packs + Cold packs |
| Product Description | LY2922470 is a potent, selective and orally available agonist of the G protein-coupled receptor 40 (GPR40) , with EC 50 s of 7 nM, 1 nM and 3 nM for human GPR40, mouse GPR40 and rat GPR40, respectively. LY2922470 reduces glucose levels along with significant increases in insulin and GLP-1 , is potential for the treatment of type 2 diabetes mellitus (T2DM) IC50& Target:EC50:7 nM (human GPR40), 1 nM (mouse GPR40), 3 nM (rat GPR40) |
| Meta | FFAR1 |