m-PEG-NHS ester - MW5000 , CAS No.92451-01-9

CAS: 92451-01-9 Cat. No.: M658882 Fórmula: (C₂H₄O)nC₇H₉NO₅ Peso molecular: 293.27 PubChem CID: 71312614

GRADE & PURITY MW5000

Synonyms

Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester | mono-Methyl polyethylene glycol 5′000 acetic acid N-succinimidyl ester | Succinimidyl ester of carboxymethyl-PEG | mPEG-SC (MW 5000) | mPEG-Succinimidyl ester (MW 5000)

Storage

Protected from light,Store at -20°C,Argon charged

Shipped In

Ice chest + Ice pads

Visão geral

The m-PEG-NHS ester (MW 5000) is a PROTAC linker belonging to the PEG class. It can be used to synthesize PROTAC molecules

m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Appearance:Solid

IC50& Target:PEGs Alkyl/ether

In Vitro:PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE

Biological Activity:m-PEG-NHS ester (MW 5000) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.

Specifications

Sinónimos

Methoxypolyethylene glycol 5,000 acetic acid N-succinimidyl ester | mono-Methyl polyethylene glycol 5′000 acetic acid N-succinimidyl ester | Succinimidyl ester of carboxymethyl-PEG | mPEG-SC (MW 5000) | mPEG-Succinimidyl ester (MW 5000)

Especificações e pureza

MW5000

Condições de armazenamento de armazenamento

Protected from light,Store at -20°C,Argon charged

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Nomes e identificadores

• Sorrisos canónicos: COCCO.C1CC(=O)N(C1=O)OC(=O)COCCO
• IUPAC Name: (2,5-dioxopyrrolidin-1-yl) 2-(2-hydroxyethoxy)acetate;2-methoxyethanol
• InChIKey: NYXRHTOXAYVBMV-UHFFFAOYSA-N
• INCHI: 1S/C8H11NO6.C3H8O2/c10-3-4-14-5-8(13)15-9-6(11)1-2-7(9)12;1-5-3-2-4/h10H,1-5H2;4H,2-3H2,1H3
• SMILES isoméricas: COCCO.C1CC(=O)N(C1=O)OC(=O)COCCO
• WGK Alemanha: 3
• PubChem CID: 71312614
• Peso molecular: 293.27

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Pyrrolidine-2-ones
• Alternative Parents: Dicarboximides Lactams Monocarboxylic acids and derivatives Dialkyl ethers Azacyclic compounds Primary alcohols Organonitrogen compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Not available
• Substituents: 2-pyrrolidone - Dicarboximide - Lactam - Carboxylic acid derivative - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Azacycle - Organonitrogen compound - Alcohol - Organic oxygen compound - Carbonyl group - Organic nitrogen compound - Organooxygen compound - Primary alcohol - Organic oxide - Hydrocarbon derivative - Aliphatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as pyrrolidine-2-ones. These are pyrrolidines which bear a C=O group at position 2 of the pyrrolidine ring.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Sensibilidade: Light Sensitive；Moisture Sensitive

Perguntas frequentes

How should this product be stored?

Store at ?20 °C, protected from light, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 92451-01-9, the molecular formula is (C2H4O)nC7H9NO5, and the molecular weight is 293.27 g/mol. InChIKey NYXRHTOXAYVBMV-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.