MAC glucuronide linker-2 - Moligand™, ≥99% , CAS No.229977-57-5

CAS: 229977-57-5 Cat. No.: M649497 Fórmula: C₂₀H₂₅NO₁₁ Peso molecular: 455.42

GRADE & PURITY Moligand™, ≥99%

Synonyms

Methyl 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronate | 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronic Acid Methyl Ester

Storage

Store at -20°C,Argon charged,Desiccated

Shipped In

Ice chest + Ice pads

Visão geral

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)

Form:Solid

IC50& Target:Cleavable Glycosidase Cleavable

Specifications

Sinónimos

Methyl 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronate | 2-Amino-4-(hydroxymethyl)phenyl 2,3,4-tri-O-acetyl-β-D-glucuronic Acid Methyl Ester

Especificações e pureza

Moligand™, ≥99%

Mecanismos bioquímicos e fisiológicos

MAC glucuronide linker-2 is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Condições de armazenamento de armazenamento

Store at -20°C,Argon charged,Desiccated

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Grau

Moligand™

Pureza

≥99%

Nomes e identificadores

• Sorrisos canónicos: CC(=O)OC1C(C(OC(C1OC(=O)C)OC2=C(C=C(C=C2)CO)N)C(=O)OC)OC(=O)C
• IUPAC Name: methyl (2S,3S,4S,5R,6S)-3,4,5-triacetyloxy-6-[2-amino-4-(hydroxymethyl)phenoxy]oxane-2-carboxylate
• InChIKey: ZAZPQJAJSIUIEY-KVIJGQROSA-N
• INCHI: 1S/C20H25NO11/c1-9(23)28-15-16(29-10(2)24)18(30-11(3)25)20(32-17(15)19(26)27-4)31-14-6-5-12(8-22)7-13(14)21/h5-7,15-18,20,22H,8,21H2,1-4H3/t15-,16-,17-,18+,20+/m0/s1
• SMILES isoméricas: CC(=O)O[C@H]1[C@@H]([C@H](O[C@H]([C@@H]1OC(=O)C)OC2=C(C=C(C=C2)CO)N)C(=O)OC)OC(=O)C
• Peso molecular: 455.42

Propriedades químicas e físicas

• Solubilidade: DMSO : 200 mg/mL (439.16 mM; Need ultrasonic)
• Sensibilidade: Moisture sensitive，Air sensitive，Heat sensitive
• Ponto de fusão (°C): 138.0-142.0 °C
• Peso molecular: 455.400 g/mol
• XLogP3: -0.100
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 12
• Rotatable Bond Count: 11
• Exact Mass: 455.143 Da
• Monoisotopic Mass: 455.143 Da
• Topological Polar Surface Area: 170.000 Ų
• Heavy Atom Count: 32
• Formal Charge: 0
• Complexity: 699.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 5
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

What is the purity of this product?

This product is supplied at ≥99% purity (chemical assay). Lot-specific values are stated on the Certificate of Analysis.

What is Moligand??

Moligand? is one of Aladdin Scientific's premium product lines, formulated for high-purity applications across multiple workflows. Compared to standard grades in the same workflow, Moligand? products typically offer tighter specifications, more rigorous QC, and stronger lot-to-lot consistency.

How should this product be stored?

Store at ?20 °C, desiccated, under argon. It is supplied under an argon blanket; reseal under inert gas after each use.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 229977-57-5, the molecular formula is C20H25NO11, and the molecular weight is 455.42 g/mol. InChIKey ZAZPQJAJSIUIEY-KVIJGQROSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.