Mal-PEG2-NHS ester , CAS No.1433997-01-3

CAS: 1433997-01-3 Cat. No.: M412495 Fórmula: C₁₅H₁₈N₂O₈ Peso molecular: 354.31 Número CE: 813-104-3

Synonyms

C70364 | SY034983 | AKOS027256652 | MFCD24539465 | LCZC2668 | Mal-PEG2-NHS ester | HY-126504 | 1433997-01-3 | SCHEMBL13525074 | A902388 | 2,5-dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate | 2,5-dioxopyrrolidin

Storage

Store at -20°C

Shipped In

Ice chest + Ice pads

Application

227,228,229

Visão geral

Information

Mal-PEG2-NHS ester is a non-cleavable ADC linker consists of a Maleimide group, 2-unit PEG and an NHS ester.

Especificações

Sinónimos

C70364 | SY034983 | AKOS027256652 | MFCD24539465 | LCZC2668 | Mal-PEG2-NHS ester | HY-126504 | 1433997-01-3 | SCHEMBL13525074 | A902388 | 2,5-dioxopyrrolidin-1-yl 3-(2-(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)ethoxy)ethoxy)propanoate | 2,5-dioxopyrrolidin

Mecanismos bioquímicos e fisiológicos

Mal-PEG2-NHS ester is a non-cleavable ADC linker consists of a Maleimide group, 2-unit PEG and an NHS ester.

Condições de armazenamento de armazenamento

Store at -20°C

Enviado em

Ice chest + Ice pads

Este produto requer transporte de cadeia fria. Serviços terrestres e outros serviços econômicos não estão disponíveis.

Nomes e identificadores

Sorrisos canónicos

C1CC(=O)N(C1=O)OC(=O)CCOCCOCCN2C(=O)C=CC2=O

IUPAC Name

(2,5-dioxopyrrolidin-1-yl) 3-[2-[2-(2,5-dioxopyrrol-1-yl)ethoxy]ethoxy]propanoate

InChIKey

KMEJZQCDHANYJV-UHFFFAOYSA-N

INCHI

1S/C15H18N2O8/c18-11-1-2-12(19)16(11)6-8-24-10-9-23-7-5-15(22)25-17-13(20)3-4-14(17)21/h1-2H,3-10H2

SMILES isoméricas

C1CC(=O)N(C1=O)OC(=O)CCOCCOCCN2C(=O)C=CC2=O

Peso molecular

354.31

Reaxy-Rn

31844514

Reaxys-RN_link_address

https://www.reaxys.com/reaxys/secured/hopinto.do?context=S&query=IDE.XRN=31844514&ln=

Taxonomic Classification

Taxonomy Tree

• Kingdom Organic compounds
  • Superclass Organoheterocyclic compounds
    • Classe Pyrrolidines
      • Subclass Pyrrolidones

• Kingdom: Organic compounds
• Superclass: Organoheterocyclic compounds
• Classe: Pyrrolidines
• Subclass: Pyrrolidones
• Intermediate Tree Nodes: Not available
• Direct Parent: Maleimides
• Alternative Parents: Pyrrolidine-2-ones N-substituted carboxylic acid imides Pyrrolines Dicarboximides Tertiary amines Lactams Amino acids and derivatives Monocarboxylic acids and derivatives Dialkyl ethers Azacyclic compounds Organic oxides Hydrocarbon derivatives Carbonyl compounds
• Molecular Framework: Aliphatic heteromonocyclic compounds
• Substituents: Maleimide - Carboxylic acid imide, n-substituted - 2-pyrrolidone - Carboxylic acid imide - Dicarboximide - Pyrroline - Tertiary amine - Amino acid or derivatives - Lactam - Azacycle - Carboxylic acid derivative - Dialkyl ether - Ether - Monocarboxylic acid or derivatives - Carbonyl group - Amine - Organic oxide - Organic oxygen compound - Hydrocarbon derivative - Organic nitrogen compound - Organonitrogen compound - Organooxygen compound - Aliphatic heteromonocyclic compound
• Descrição: This compound belongs to the class of organic compounds known as maleimides. These are compounds containing a 2,5-pyrroledione moiety.
• External Descriptors: Not available

Data sources

1. Djoumbou Feunang Y, Eisner R, Knox C, Chepelev L, Hastings J, Owen G, Fahy E, Steinbeck C, Subramanian S, Bolton E, Greiner R, and Wishart DS. ClassyFire: Automated Chemical Classification With A Comprehensive, Computable Taxonomy. Journal of Cheminformatics, 2016, 8:61.

DOI: 10.1186/s13321-016-0174-y

Propriedades químicas e físicas

• Solubilidade: Solubility (25°C) In vitro
• Peso molecular: 354.310 g/mol
• XLogP3: -1.900
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 11
• Exact Mass: 354.106 Da
• Monoisotopic Mass: 354.106 Da
• Topological Polar Surface Area: 120.000 Ų
• Heavy Atom Count: 25
• Formal Charge: 0
• Complexity: 566.000
• Isotope Atom Count: 0
• Defined Atom Stereocenter Count: 0
• Undefined Atom Stereocenter Count: 0
• Defined Bond Stereocenter Count: 0
• Undefined Bond Stereocenter Count: 0
• The total count of all stereochemical bonds: 0
• Covalently-Bonded Unit Count: 1

Perguntas frequentes

How should this product be stored?

Store at ?20 °C. Freezer storage is required to maintain the specified shelf life.

How is this product shipped?

This product ships in an insulated container with ice pads. Unpack on arrival and transfer it to the storage condition stated above.

What are the CAS number, molecular formula and molecular weight?

The CAS Number is 1433997-01-3, the molecular formula is C15H18N2O8, and the molecular weight is 354.31 g/mol. InChIKey KMEJZQCDHANYJV-UHFFFAOYSA-N.

What documentation is provided?

Available product documentation, including Certificates of Analysis (COA), Safety Data Sheets (SDS), and specification sheets, is shown in the product document area. Document availability and access follow the current site policy.